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BMS-299897

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845786

BMS-299897 is a potent; brain-permeant gamma-secretase inhibitor (IC50 = 12 nM). Inhibits Abeta40 and Abeta42 formation in vitro  (IC50 values are 7.4 and 7.9 nM respectively) and reduces Abeta in the brain; plasma and cerebrospinal fluid in vivo.… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BMS-299897, Biochemical
Full Product Name
BMS-299897
Product Gene Name
BMS-299897 biochemical
Product Synonym Names
(R)-4- (2- (1- (4-chloro-N- (2; 5-difluorophenyl) phenylsulfonamido) ethyl)-5-fluorophenyl) butanoic acid
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
511.94
Salt Form
No
CAS Number
290315-45-6
Cell-Permeable
Yes
Reconstitution
DMSO (>40 mg/ml)
SMILES
CC(C1=C(C=C(C=C1)F)CCCC(=O)O)N(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl
InChi
InChI=1S/C24H21ClF3NO4S/c1-15(21-11-7-18(26)13-16(21)3-2-4-24(30)31)29(23-14-19(27)8-12-22(23)28)34(32,33)20-9-5-17(25)6-10-20/h5-15H,2-4H2,1H3,(H,30,31)/t15-/m1/s1
InChi Key
IZAOBRWCUGOKNH-OAHLLOKOSA-N

Structure of BMS-299897 biochemical

BMS-299897 Biochemical – Cat# MBS845786

Other Notes

Small volumes of BMS-299897 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMS-299897 purchase

MBS845786 is a biochemical targeting BMS-299897.
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