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AGI-6780

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845803

AGI-6780 is a potent; selective inhibitor of mutant Isocitrate dehydrogenase 2 (IDH2) (IC50= 23 nM). It binds allosterically at the dimer interface of mutant IDH2-R140Q; inhibiting 2-hydroxyglutarate (2-HG) formation in human glioblastoma U87 and TF-1 cells… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AGI-6780, Biochemical
Full Product Name
AGI-6780
Product Gene Name
AGI-6780 biochemical
Product Synonym Names
N-cyclopropyl-4- (thiophen-3-yl)-3- (3- (3- (trifluoromethyl) phenyl) ureido) benzenesulfonamide
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
481.51
Salt Form
No
Molecular Formula
C21H18F3N3O3S2
CAS Number
1432660-47-3 
Cell-Permeable
Yes
Reconstitution
DMSO (~30 mg/ml)

Other Notes

Small volumes of AGI-6780 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGI-6780 purchase

MBS845803 is a biochemical targeting AGI-6780.
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