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AEE-788

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845837

AEE-788 is a potent EGFR and VEGFR inhibitor (IC50 values are 2; 6; 59; 77; 160 and 330 nM for EGFR; ErbB2; VEGFR-1; VEGFR-2; ErbB4 and VEGFR-3 respectively). Also inhibits c-Abl; c-Fms and c-Src (IC50 values are 52; 60 and 61 nM respectively). Inhibits tumor… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AEE-788, Biochemical
Full Product Name
AEE-788
Product Gene Name
AEE-788 biochemical
Product Synonym Names
6-[4-[ (4-Ethylpiperazin-1-yl) methyl]phenyl]-N-[ (1R)-1-phenylethyl]-7H-pyrrolo[2; 3-d]pyrimidin-4-amine; AEE788; NVP-AEE788
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
440.58
Salt Form
No
Molecular Formula
C27H32N6
CAS Number
497839-62-0
Cell-Permeable
Yes
Reconstitution
DMSO (>50 mg/ml)

Other Notes

Small volumes of AEE-788 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AEE-788 purchase

MBS845837 is a biochemical targeting AEE-788.
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