• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GLP-1R Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS845943

Polyclonal Antibody against AGTR4.This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Currently; six glucagon-like peptide-1 receptor agonists (GLP-1RAs) are approved for… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
GLP-1R, Polyclonal Antibody
Full Product Name
GLP-1R Polyclonal Antibody
Product Gene Name
anti-GLP-1R antibody
Product Synonym Names
GLP1R; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Colorless liquid
100 ug (1mg/ml) of antibody containing 50% glycerol; 0.5% BSA and 0.02% sodium azide
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.
Molecular Weight
52,877 Da
3D Structure
ModBase 3D Structure for P32301
Immunogen
Synthesized peptide derived from the Internal region of human GLP-1R (80-160aa).

Product Categories/Family for anti-GLP-1R antibody

GPCR
Applications Tested/Suitable for anti-GLP-1R antibody
Western Blot (WB); Immunohistochemistry (IHC); ELISA (EIA)
Application Notes for anti-GLP-1R antibody
WB: 1:500-1:2000
IF: 1:200-1:1000
ELISA: 1:5000

Other Notes

Small volumes of anti-GLP-1R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLP-1R purchase

MBS845943 is an antibody targeting GLP-1R. Also known as GLP-1R Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GLP-1R. It may not necessarily be applicable to this product.

NCBI GI #
7110605
NCBI GeneID
25051
NCBI Accession #
NP_036860.1
UniProt Primary Accession #
P32301
UniProt Secondary Accession #
Q64073; Q6LD83
UniProt Related Accession #
P32301
GenBank Nucleotide #
NM_012728.1
NCBI Official Full Name
glucagon-like peptide 1 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 1 receptor
NCBI Official Symbol
Glp1r
NCBI Official Synonym Symbols
Glip; RATGL1RCP
UniProt Protein Name
Glucagon-like peptide 1 receptor
Protein Family
Glucagon-like peptide 1 receptor
UniProt Gene Name
Glp1r
UniProt Synonym Gene Names
Glpr; GLP-1 receptor; GLP-1-R; GLP-1R
NCBI Protein Information
glucagon-like peptide 1 receptor

NCBI Summary for GLP-1R

induces insulin secretion; mediates neuroendocrine signaling of feeding behavior; mediates cardiovascular response and increased blood pressure [RGD, Feb 2006]

UniProt Comments for GLP-1R

GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 20p12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide hormone binding; peptide receptor activity; peptide receptor activity, G-protein coupled

Biological Process: associative learning; cAMP-mediated signaling; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; hormone secretion; insulin secretion; learning and/or memory; memory; negative regulation of apoptosis; negative regulation of neuron apoptosis; neuropeptide signaling pathway; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of glucose import; positive regulation of heart contraction; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; regulation of calcium ion transport; regulation of heart contraction; regulation of insulin secretion; release of sequestered calcium ion into cytosol; response to glucose stimulus
Show more

Research Articles on GLP-1R

1. The vasodilatation due to glucagon evokes via the glucagon-receptor, but also via the receptor for GLP-1, and it is endothelium-independent.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GLP-1R antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Integration Of Energy Metabolism Pathway antibodies  Integration Of Energy Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Regulation Of Insulin Secretion Pathway antibodies  Regulation Of Insulin Secretion Pathway Diagram
 Regulation Of Insulin Secretion By Glucagon-like Peptide-1 Pathway antibodies  Regulation Of Insulin Secretion By Glucagon-like Peptide-1 Pathway Diagram

Diseases associated with anti-GLP-1R antibody

 Disease Name  Pubmed Publications
 Obesity Antibodies  >12 publications with GLP-1R and Obesity
 Hyperglycemia Antibodies  >8 publications with GLP-1R and Hyperglycemia
 Diabetes Mellitus, Type 2 Antibodies  >7 publications with GLP-1R and Diabetes Mellitus, Type 2
 Disease Models, Animal Antibodies  >5 publications with GLP-1R and Disease Models, Animal
 Glucose Intolerance Antibodies  >5 publications with GLP-1R and Glucose Intolerance
 Nervous System Diseases Antibodies  >4 publications with GLP-1R and Nervous System Diseases
 Neoplasms Antibodies  >3 publications with GLP-1R and Neoplasms
 Insulin Resistance Antibodies  >3 publications with GLP-1R and Insulin Resistance
 Diabetes Mellitus, Experimental Antibodies  >2 publications with GLP-1R and Diabetes Mellitus, Experimental
 Reperfusion Injury Antibodies  >2 publications with GLP-1R and Reperfusion Injury

Organs/Tissues associated with anti-GLP-1R antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >17 publications with GLP-1R and Pancreas
 Lung Antibodies  >1 publications with GLP-1R and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000