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KI67 Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846013

Rabbit monoclonal antibody to detect KI67 in human and mouse samples.Ki-67 is a nuclear protein that is expressed in proliferating cells and may be required for maintaining cell proliferation. Ki-67 has been used as a marker for cell proliferation of solid… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
KI67, Monoclonal Antibody
Full Product Name
Anti-KI67 Rabbit Monoclonal Antibody
Product Gene Name
Product Synonym Gene Name
MKI67
Product Synonym Names
KIA; KI-67; MKI67
Clonality
Monoclonal
Isotype
IgG
Clone Number
RM227
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Colorless liquid
In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purity/Purification
Affinity purified using protein A
Preparation and Storage
Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.
Molecular Weight
319,444 Da
OMIM
X65550 mRNA
3D Structure
ModBase 3D Structure for P46013
Immunogen
A peptide corresponding to the internal region of human Ki67
Applications Tested/Suitable for anti-KI67 antibody
Immunohistochemistry (IHC); Western Blot (WB)
Application Notes for anti-KI67 antibody
IHC: 1:100- 1:400 dilution
WB: 1:100- 1:500 dilution

Testing Data of anti-KI67 antibody

Rabbit Anti-KI67 Monoclonal Antibody – Cat# MBS846013

Other Notes

Small volumes of anti-KI67 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KI67 purchase

MBS846013 is an antibody targeting KI67. Also known as Anti-KI67 Rabbit Monoclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KI67. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
proliferation marker protein Ki-67 isoform 2
NCBI Official Synonym Full Names
marker of proliferation Ki-67
NCBI Official Symbol
MKI67
NCBI Official Synonym Symbols
KIA; MIB-; MIB-1; PPP1R105
UniProt Protein Name
Proliferation marker protein Ki-67
UniProt Synonym Protein Names
Antigen identified by monoclonal antibody Ki-67
UniProt Gene Name
MKI67
UniProt Synonym Gene Names
Antigen KI-67Curated; Antigen Ki67Curated
NCBI Protein Information
proliferation marker protein Ki-67; antigen KI-67

NCBI Summary for KI67

This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]

UniProt Comments for KI67

KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers.

Protein type: Cell cycle regulation; Nucleolus

Chromosomal Location of Human Ortholog: 10q26.2

Cellular Component: condensed chromosome; membrane; nuclear body; nucleolus; nucleus

Molecular Function: protein binding; protein C-terminus binding; RNA binding

Biological Process: cell proliferation; regulation of chromosome segregation; regulation of mitosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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