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STEAP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846048

Polyclonal antibody to detect endogenous levels of STEAP2 in human; mouse and rat.The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of the STEAP family. The STEAP proteins are metalloreductases that has the ability to reduce both… More details

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Product Overview

Product Name
STEAP2, Polyclonal Antibody
Full Product Name
Anti-STEAP2 Antibody
Product Gene Name
Product Synonym Names
PCANAP1; STAMP1; Metalloreductase STEAP2; Prostate cancer-associated protein 1; Protein up-regulated in metastatic prostate cancer; PUMPCn; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Colorless liquid
In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
Purity/Purification
Affinity Purified
Preparation and Storage
Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.
Molecular Weight
47,916 Da
OMIM
AY008444 mRNA
3D Structure
ModBase 3D Structure for Q8NFT2
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human STEAP2
Applications Tested/Suitable for anti-STEAP2 antibody
Western Blot (WB); Immunohistochemistry (IHC); Immunofluorescence (IF); Immunocytochemistry (ICC)
Application Notes for anti-STEAP2 antibody
WB: 1:500- 1:2000
IHC: 1:50- 1:200
IF/IC: 1:50- 1:100

Testing Data of anti-STEAP2 antibody

Rabbit Anti-STEAP2 Polyclonal Antibody – Cat# MBS846048

Other Notes

Small volumes of anti-STEAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STEAP2 purchase

MBS846048 is an antibody targeting STEAP2. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STEAP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
metalloreductase STEAP2 isoform a
NCBI Official Synonym Full Names
STEAP2 metalloreductase
NCBI Official Symbol
STEAP2
NCBI Official Synonym Symbols
STMP; IPCA1; PUMPCn; STAMP1; PCANAP1
UniProt Protein Name
Metalloreductase STEAP2
UniProt Synonym Protein Names
Prostate cancer-associated protein 1; Protein up-regulated in metastatic prostate cancer; PUMPCn; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1
Protein Family
UniProt Gene Name
STEAP2
UniProt Synonym Gene Names
PCANAP1; STAMP1; PUMPCn
NCBI Protein Information
metalloreductase STEAP2

NCBI Summary for STEAP2

This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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UniProt Comments for STEAP2

STEAP2: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Belongs to the STEAP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.16.1.-; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase; Vesicle

Chromosomal Location of Human Ortholog: 7q21.13

Cellular Component: cytosol; early endosome; integral to Golgi membrane; integral to plasma membrane; plasma membrane; trans-Golgi network transport vesicle

Molecular Function: cupric reductase activity; transporter activity

Biological Process: copper ion import; endocytosis; Golgi to plasma membrane transport; regulated secretory pathway; response to hormone stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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