AMPKbeta1 Antibody – Rabbit Polyclonal

Polyclonal antibody to detect endogenous levels of AMPKbeta1 protein when phosphorylated at Ser182 in human; mouse and rat.
Non-catalytic subunit of AMP-activated protein kinase (AMPK); an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels; AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein; carbohydrate and lipid biosynthesis; as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes; and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles; via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1; PRKAG2 or PRKAG3).

Small volumes of anti-AMPKbeta1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS846126 is an antibody targeting AMPKbeta1. Also known as Phospho-AMPKbeta1 (Ser182) Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.