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MCC950 (Free base)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846178

MCC950 is a potent and selective NLRP3 inflammasome inhibitor. It blocks the release of IL-1beta in macrophages primed with LPS and activated with ATP or nigericin; but it does not inhibit NLRP1; NLRC4; AIM2; TLR2 signaling or priming of NLRP3. Also… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MCC950, Biochemical
Full Product Name
MCC950 (Free base)
Product Gene Name
MCC950 biochemical
Product Synonym Names
N-[[ (1; 2; 3; 5; 6; 7-Hexahydro-s-indacen-4-yl) amino]carbonyl]-4- (1-hydroxy-1-methylethyl)-2-furansulfonamide; CP-456; 773; CRID3
Form/Format
Light yellow to yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
404.48
Salt Form
No
Molecular Formula
C20H24N2O5S
CAS Number
210826-40-7
Cell-Permeable
Yes
Reconstitution
DMSO (>35 mg/ml)
SMILES
CC(C)(C1=COC(=C1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4)O
InChi
InChI=1S/C20H24N2O5S/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23)
InChi Key
HUUSXLKCTQDPGL-UHFFFAOYSA-N

Structure of MCC950 biochemical

MCC950 (Free base) Biochemical – Cat# MBS846178

Other Notes

Small volumes of MCC950 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MCC950 purchase

MBS846178 is a biochemical targeting MCC950. Also known as MCC950 (Free base).
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