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JNJ-42041935

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846219

JNJ-42041935 is a HIF-PHD (Hypoxia-inducible factor- prolyl hydroxylase) inhibitor. JNJ-42041935 is a selective; 2-OG (2-oxoglutarate) competitive; and reversible inhibitor of PHD enzymes (pKis = 7.91; 7.29; and 7.65 for PHD1; 2; and 3; respectively). It is… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
JNJ-42041935, Biochemical
Full Product Name
JNJ-42041935
Product Gene Name
Product Synonym Names
1-[6-chloro-5- (trifluoromethoxy)-1H-benzimidazol-2-yl]-1H-pyrazole-4-carboxylic acid
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
346.65
Salt Form
No
CAS Number
1193383-09-3
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
C1=C2C(=CC(=C1Cl)OC(F)(F)F)N=C(N2)N3C=C(C=N3)C(=O)O
InChi
1S/C12H6ClF3N4O3/c13-6-1-7-8(2-9(6)23-12(14,15)16)19-11(18-7)20-4-5(3-17-20)10(21)22/h1-4H,(H,18,19)(H,21,22)
InChi Key
FXHHASJVTYRJHH-UHFFFAOYSA-N

Other Notes

Small volumes of JNJ-42041935 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS846219 is a biochemical targeting JNJ-42041935.
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