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K858

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846220

K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC50 = 1.3 uM) and an antitumor agent. Induces cell death in cancer cells; blocks centrosome separation; activates the spindle checkpoint; and induces mitotic arrest in cells accompanied by… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
K858, Biochemical
Full Product Name
K858
Product Gene Name
Product Synonym Names
N- (4-acetyl-5-methyl-5-phenyl-4; 5-dihydro-1; 3; 4-thiadiazol-2-yl) acetamide
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
277.34
Salt Form
No
CAS Number
72926-24-0
Cell-Permeable
Yes
Reconstitution
DMSO (>20 mg/ml)
SMILES
CC(=O)NC1=NN(C(S1)(C)C2=CC=CC=C2)C(=O)C
InChi
InChI=1S/C13H15N3O2S/c1-9(17)14-12-15-16(10(2)18)13(3,19-12)11-7-5-4-6-8-11/h4-8H,1-3H3,(H,14,15,17)
InChi Key
JEFVYQYZCAVNTP-UHFFFAOYSA-N

Structure of K858 biochemical

K858 Biochemical – Cat# MBS846220

Other Notes

Small volumes of K858 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for K858 purchase

MBS846220 is a biochemical targeting K858.
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