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KM-11060

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846223

KM-11060 is a mutated F508del cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It increases the amount of functional CFTR at the plasma membrane (~75%) and Inhibits PDE5 (phosphodiesterase type 5) activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
KM-11060, Biochemical
Full Product Name
KM-11060
Product Gene Name
KM-11060 biochemical
Product Synonym Names
7-Chloro-4-[4-[4-chlorophenyl) sulfonyl]-1-piperazinyl]quinoline
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
422.33
Salt Form
No
CAS Number
774549-97-2
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
C1CN(CCN1C2=C3C=CC(=CC3=NC=C2)Cl)S(=O)(=O)C4=CC=C(C=C4)Cl
InChi
InChI=1S/C19H17Cl2N3O2S/c20-14-1-4-16(5-2-14)27(25,26)24-11-9-23(10-12-24)19-7-8-22-18-13-15(21)3-6-17(18)19/h1-8,13H,9-12H2
InChi Key
GIEHIZKCIZLXLF-UHFFFAOYSA-N

Structure of KM-11060 biochemical

KM-11060 Biochemical – Cat# MBS846223

Other Notes

Small volumes of KM-11060 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KM-11060 purchase

MBS846223 is a biochemical targeting KM-11060.
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