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GSK2330672 (3- ({[ (3R)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846246

GSK2330672 is a highly selective; potent; nonabsorbable ASBT (Apical Sodium dependent bile acid transporter) inhibitor (IC50 = 42 nM). It lowers glucose in an animal model of type 2 diabetes. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GSK2330672, Biochemical
Full Product Name
GSK2330672
Product Gene Name
Product Synonym Names
3- ({[ (3R; 5R)-3-Butyl-3-ethyl-7-methoxy-1; 1-dioxido-5-phenyl-2; 3; 4; 5-tetrahydro-1; 4-benzothiazepin-8-yl]methyl}amino) pentanedioic acid
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
546.68
Salt Form
No
CAS Number
1345982-69-5
Cell-Permeable
Yes
Reconstitution
DMSO (>20 mg/ml)
SMILES
CCCCC1(CS(=O)(=O)C2=CC(=C(C=C2C(N1)C3=CC=CC=C3)OC)CNC(CC(=O)O)CC(=O)O)CC
InChi
InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15-26(33)34)23(37-3)16-22(24)27(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27,29-30H,4-6,12,14-15,17-18H2,1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1
InChi Key
CZGVOBIGEBDYTP-VSGBNLITSA-N

Other Notes

Small volumes of GSK2330672 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK2330672 purchase

MBS846246 is a biochemical targeting GSK2330672.
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