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Skepinone-L (2-[ (2)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846254

Skepinone-L is a potent; ATP-competitive inhibitor of p38 MAPK isoform p38alpha (IC50 = 5 nM) and p38beta (97% inhibition at 1 uM). It has little effect on a range of other kinases; including p38gamma and p38delta. Skepinone-L dose-dependently blocks the… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Skepinone-L, Biochemical
Full Product Name
Skepinone-L
Product Synonym Names
2-[ (2; 4-difluorophenyl) amino]-7-[ (2R)-2; 3-dihydroxypropoxy]-10; 11-dihydro-5H-dibenzo[a; d]cyclohepten-5-one
Form/Format
Yellow solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
425.4
Salt Form
No
CAS Number
1221485-83-1
Cell-Permeable
Yes
Reconstitution
DMSO (~15 mg/ml)
SMILES
C1CC2=C(C=CC(=C2)NC3=C(C=C(C=C3)F)F)C(=O)C4=C1C=CC(=C4)OCC(CO)O
InChi
InChI=1S/C24H21F2NO4/c25-16-4-8-23(22(26)10-16)27-17-5-7-20-15(9-17)2-1-14-3-6-19(11-21(14)24(20)30)31-13-18(29)12-28/h3-11,18,27-29H,1-2,12-13H2/t18-/m1/s1
InChi Key
HXMGCTFLLWPVFM-GOSISDBHSA-N

Structure of Skepinone-L biochemical

Skepinone-L 2-[ (2 Biochemical – Cat# MBS846254

Other Notes

Small volumes of Skepinone-L biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Skepinone-L purchase

MBS846254 is a biochemical targeting Skepinone-L.
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