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(Z)-4-Hydroxytamoxifen

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846258

(Z)-4-Hydroxytamoxifen is a metabolite of Tamoxifen; acts as a potent estrogen receptor antagonist. Displays more potency than the parent compound. Also activates intein-linked inactive Cas9; reducing off-target CRISPR-mediated gene editing. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
(Z)-4-Hydroxytamoxifen, Biochemical
Full Product Name
(Z)-4-Hydroxytamoxifen
Product Synonym Names
4-[ (1Z)-1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; 4-OH-TAM
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
387.51
Salt Form
No
CAS Number
68047-06-3
Cell-Permeable
Yes
Reconstitution
DMSO (>35 mg/ml) or H2O (>10 mg/ml)
SMILES
CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
InChi
InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-
InChi Key
TXUZVZSFRXZGTL-QPLCGJKRSA-N

Other Notes

Small volumes of (Z)-4-Hydroxytamoxifen biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS846258 is a biochemical targeting (Z)-4-Hydroxytamoxifen.
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