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Apilimod mesylate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846272

Apilimod is a small molecule that inhibits IL-12 and IL-23 production- cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c-Rel. It suppresses the Th1; but not the Th2; response; resulting in reduced… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Apilimod mesylate, Biochemical
Full Product Name
Apilimod mesylate
Product Synonym Names
(E)-4- (6- (2- (3-methylbenzylidene) hydrazinyl)-2- (2- (pyridin-2-yl) ethoxy) pyrimidin-4-yl) morpholine dimethanesulfonate
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and moisture.
Molecular Weight
610.7
Salt Form
No
CAS Number
870087-36-8 
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC1=CC=CC(=C1)C=NNC2=NC(=NC(=C2)N3CCOCC3)OCCC4=CC=CC=N4.CS(=O)(=O)O.CS(=O)(=O)O
InChi
InChI=1S/C23H26N6O2.2CH4O3S/c1-18-5-4-6-19(15-18)17-25-28-21-16-22(29-10-13-30-14-11-29)27-23(26-21)31-12-8-20-7-2-3-9-24-20;2*1-5(2,3)4/h2-7,9,15-17H,8,10-14H2,1H3,(H,26,27,28);2*1H3,(H,2,3,4)/b25-17+;;
InChi Key
GAJWNIKZLYZYSY-OKUPSQOASA-N

Other Notes

Small volumes of Apilimod mesylate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Apilimod mesylate purchase

MBS846272 is a biochemical targeting Apilimod mesylate.
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