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NKL 22 (MDK-4154)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846276

NKL 22 (also known as MDK-4154) is a cell-permeable compound that acts as a FXN- (frataxin gene) specific HDAC (histone deacetylase) inhibitor. It reverses the silencing of FXN transcription in FRDA (Friedreich's ataxia) cells due to hypoacetylation of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
NKL 22, Biochemical
Full Product Name
NKL 22 (MDK-4154)
Product Gene Name
Product Synonym Names
N1- (2-aminophenyl)-N7-phenylheptanediamide
Form/Format
Beige to pale white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
325.4
Salt Form
No
CAS Number
537034-15-4
Cell-Permeable
Yes
Reconstitution
DMSO (100 mg/ml)
SMILES
C1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N
InChi
1S/C19H23N3O2/c20-16-11-7-8-12-17(16)22-19(24)14-6-2-5-13-18(23)21-15-9-3-1-4-10-15/h1,3-4,7-12H,2,5-6,13-14,20H2,(H,21,23)(H,22,24)
InChi Key
ZAIULUYKQLVQFH-UHFFFAOYSA-N

Structure of NKL 22 biochemical

NKL 22 (MDK-4154) Biochemical – Cat# MBS846276

Other Notes

Small volumes of NKL 22 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKL 22 purchase

MBS846276 is a biochemical targeting NKL 22. Also known as NKL 22 (MDK-4154).
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