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GNF-7 (N-[3-[1)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846282

GNF-7 is a multi-targeted kinase inhibitor that inhibits activated CDC42 kinase 1 (ACK1) and germinal center kinase (GCK) inducing cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. It also displays significant in vivo efficacy… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GNF-7, Biochemical
Full Product Name
GNF-7
Product Gene Name
Product Synonym Names
N-[3-[1; 4-Dihydro-1-methyl-7-[ (6-methyl-3-pyridinyl) amino]-2-oxopyrimido[4; 5-d]pyrimidin-3 (2H)-yl]-4-methylphenyl]-3- (trifluoromethyl) benzamide
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
547.53
Salt Form
No
CAS Number
839706-07-9
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CN=C(C=C5)C
InChi
1S/C28H24F3N7O2/c1-16-7-9-21(34-25(39)18-5-4-6-20(11-18)28(29,30)31)12-23(16)38-15-19-13-33-26(36-24(19)37(3)27(38)40)35-22-10-8-17(2)32-14-22/h4-14H,15H2,1-3H3,(H,34,39)(H,33,35,36)
InChi Key
SZNYUUZOQHNEKB-UHFFFAOYSA-N

Structure of GNF-7 biochemical

GNF-7 N-[3-[1 Biochemical – Cat# MBS846282

Other Notes

Small volumes of GNF-7 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNF-7 purchase

MBS846282 is a biochemical targeting GNF-7.
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