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AZ-3146

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846288

AZ 3146 is a potent and selective Mps1 (monopolar spindle 1) kinase inhibitor (IC50 = 35 nM). Shows selectivity over 46 other kinases including aurora kinase B and Cdk1. AZ 3146 overrides spindle assembly checkpoint and also interferes with chromosome… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AZ-3146, Biochemical
Full Product Name
AZ-3146
Product Gene Name
AZ-3146 biochemical
Product Synonym Names
9-Cyclopentyl-2-[[2-methoxy-4-[ (1-methylpiperidin-4-yl) oxy]-phenyl]amino]-7-methyl-7; 9-dihydro-8H-purin-8-one
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
452.55
Salt Form
No
CAS Number
1124329-14-1
Cell-Permeable
Yes
Reconstitution
DMSO (>10 mg/ml))
SMILES
CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC
InChi
1S/C24H32N6O3/c1-28-12-10-17(11-13-28)33-18-8-9-19(21(14-18)32-3)26-23-25-15-20-22(27-23)30(24(31)29(20)2)16-6-4-5-7-16/h8-9,14-17H,4-7,10-13H2,1-3H3,(H,25,26,27)
InChi Key
YUKWVHPTFRQHMF-UHFFFAOYSA-N

Structure of AZ-3146 biochemical

AZ-3146 Biochemical – Cat# MBS846288

Other Notes

Small volumes of AZ-3146 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZ-3146 purchase

MBS846288 is a biochemical targeting AZ-3146.
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