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PF-04418948

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846311

PF-04418948 is a potent EP2 receptor antagonist with an IC50 of 16 nM for human EP2 receptors. It also displays greater selectivity for EP2 receptors over EP1; 3; 4; DPI and CRTH2 receptors. It inhibits PGE2 induced increase in intracellular cAMP. In vivo… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-04418948, Biochemical
Full Product Name
PF-04418948
Product Gene Name
PF-04418948 biochemical
Product Synonym Names
1- (4-fluorobenzoyl)-3-[ (6-methoxynaphthalen-2-yl) oxymethyl]azetidine-3-carboxylic acid
Form/Format
White solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
409.41
Salt Form
No
CAS Number
1078166-57-0
Cell-Permeable
Yes
Reconstitution
DMSO (>40 mg/ml)
SMILES
COC1=CC2=C(C=C1)C=C(C=C2)OCC3(CN(C3)C(=O)C4=CC=C(C=C4)F)C(=O)O
InChi
1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)
InChi Key
LWJGMYMNSNVCEM-UHFFFAOYSA-N

Structure of PF-04418948 biochemical

PF-04418948 Biochemical – Cat# MBS846311

Other Notes

Small volumes of PF-04418948 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-04418948 purchase

MBS846311 is a biochemical targeting PF-04418948.
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