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Bardoxolone (2-cyano-3)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846313

Bardoxolone is a synthetic oleanane triterpenoid that inhibits cellular iNOS production when stimulated by IFNg; TNF-alpha and IL-1. It is Reata's investigational lead molecule for CKD (chronic kidney disease). It is a potent inducer of the transcription… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Bardoxolone, Biochemical
Full Product Name
Bardoxolone
Product Synonym Names
2-cyano-3; 12-dioxo-oleana-1; 9 (11)-dien-28-oic acid; RTA 402; CDDO
Form/Format
Light brown solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
491.66
Salt Form
No
CAS Number
218600-44-3
Cell-Permeable
Yes
Reconstitution
DMSO (>4.5 mg/ml)
SMILES
CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)C(=O)O)C
InChi
1S/C31H41NO4/c1-26(2)10-12-31(25(35)36)13-11-30(7)23(19(31)16-26)20(33)14-22-28(5)15-18(17-32)24(34)27(3,4)21(28)8-9-29(22,30)6/h14-15,19,21,23H,8-13,16H2,1-7H3,(H,35,36)/t19-,21-,23-,28-,29+,30+,31-/m0/s1
InChi Key
TXGZJQLMVSIZEI-UQMAOPSPSA-N

Other Notes

Small volumes of Bardoxolone biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bardoxolone purchase

MBS846313 is a biochemical targeting Bardoxolone.
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