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(R; R)-Hymeglusin ((2E)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846386

(R; R)-Hymeglusin is a specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. It is a fungal beta-lactone that inhibits… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
(R; R)-Hymeglusin, Biochemical
Full Product Name
(R; R)-Hymeglusin
Product Synonym Names
(2E; 4E; 7R)-11-[ (2R; 3R)-3- (Hydroxymethyl)-4-oxooxetan-2-yl]-3; 5; 7-trimethylundeca-2; 4-dienoic acid
Form/Format
White to off-white solid
Purity/Purification
>=95% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
324.41
Salt Form
No
CAS Number
29066-42-0
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC(CCCCC1C(C(=O)O1)CO)CC(=CC(=CC(=O)O)C)C
InChi
InChI=1S/C18H28O5/c1-12(8-13(2)9-14(3)10-17(20)21)6-4-5-7-16-15(11-19)18(22)23-16/h9-10,12,15-16,19H,4-8,11H2,1-3H3,(H,20,21)/b13-9+,14-10+/t12-,15-,16-/m1/s1
InChi Key
ODCZJZWSXPVLAW-KXCGKLMDSA-N

Other Notes

Small volumes of (R; R)-Hymeglusin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS846386 is a biochemical targeting (R; R)-Hymeglusin.
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