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PF-562271 besylate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846395

F-562271 is an ATP-competitive; reversible inhibitor of FAK (IC50 = 1.5 nM). It displays 10-fold reduced potency for PYK2 (IC50 = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC?? value of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-562271, Biochemical
Full Product Name
PF-562271 besylate
Product Gene Name
PF-562271 biochemical
Product Synonym Names
N-[3-[[[2-[ (2; 3-dihydro-2-oxo-1H-indol-5-yl) amino]-5- (trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide; monobenzenesulfonate
Form/Format
Off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and moisture.
Molecular Weight
665.66
Salt Form
Yes
CAS Number
939791-38-5
Cell-Permeable
Yes
Reconstitution
DMSO (>20 mg/ml)
SMILES
CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.C1=CC=C(C=C1)S(=O)(=O)O
InChi
InChI=1S/C21H20F3N7O3S.C6H6O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16;7-10(8,9)6-4-2-1-3-5-6/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30);1-5H,(H,7,8,9)
InChi Key
LKLWTLXTOVZFAE-UHFFFAOYSA-N

Structure of PF-562271 biochemical

PF-562271 besylate Biochemical – Cat# MBS846395

Other Notes

Small volumes of PF-562271 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-562271 purchase

MBS846395 is a biochemical targeting PF-562271. Also known as PF-562271 besylate.
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