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PF-04447943

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846405

PF-04447943 is a potent; brain-penetrant and selective inhibitor of PDE9 (Phosphodiesterase 9) (Ki of 2.8; 4.5 and 18 nM for human; rhesus and rat recombinant PDE9 respectively). Displays high selectivity for PDE9 versus PDEs1-8 and 10-11. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PF-04447943, Biochemical
Full Product Name
PF-04447943
Product Gene Name
PF-04447943 biochemical
Product Synonym Names
N-[2- (diethylamino) ethyl]-2-[[ (4-fluorophenyl) methyl]thio]-4; 5; 6; 7-tetrahydro-4-oxo-N-[[4'- (trifluoromethyl) [1; 1'-biphenyl]-4-yl]methyl]-1H-Cyclopentapyrimidine-1-acetamide; SB-480848
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
395.46
Molecular Formula
C20H25N7O2
CAS Number
1082744-20-4
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC1CN(CC1C2=NC(=O)C3=CNN(C3=N2)C4CCOCC4)CC5=NC=CC=N5
InChi
InChI=1S/C20H25N7O2/c1-13-10-26(12-17-21-5-2-6-22-17)11-16(13)18-24-19-15(20(28)25-18)9-23-27(19)14-3-7-29-8-4-14/h2,5-6,9,13-14,16,23H,3-4,7-8,10-12H2,1H3/t13-,16-/m1/s1
InChi Key
ACXPOEVOYNJCHF-CZUORRHYSA-N

Structure of PF-04447943 biochemical

PF-04447943 Biochemical – Cat# MBS846405

Other Notes

Small volumes of PF-04447943 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-04447943 purchase

MBS846405 is a biochemical targeting PF-04447943.
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