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Alpelisib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846411

Alpelisib (also known as BYL719); is a potent and selective phosphatidylinositol-3 kinase alpha inhibitor. It inhibits P110alpha; p110beta; p110delta; and p110g with IC50 values of 5 nM; 1.2 uM; 0.29 uM and 0.25 uM; respectively; in biochemical assays. It… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Alpelisib, Biochemical
Full Product Name
Alpelisib
Product Synonym Names
(S)-N1- (4-methyl-5- (2- (1; 1; 1-trifluoro-2-methylpropan-2-yl) pyridin-4-yl) thiazol-2-yl) pyrrolidine-1; 2-dicarboxamide; BYL719
Form/Format
White to off-white solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
441.47
Salt Form
No
Molecular Formula
C19H22F3N5O2S 
CAS Number
1217486-61-7 
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F
InChi
InChI=1S/C19H22F3N5O2S/c1-10-14(11-6-7-24-13(9-11)18(2,3)19(20,21)22)30-16(25-10)26-17(29)27-8-4-5-12(27)15(23)28/h6-7,9,12H,4-5,8H2,1-3H3,(H2,23,28)(H,25,26,29)/t12-/m0/s1
InChi Key
STUWGJZDJHPWGZ-LBPRGKRZSA-N

Structure of Alpelisib biochemical

Alpelisib Biochemical – Cat# MBS846411

Other Notes

Small volumes of Alpelisib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Alpelisib purchase

MBS846411 is a biochemical targeting Alpelisib.
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