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DP-4978 (1- (3)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846428

DP-4978 is a potent and selective pan-RAF inhibitor with potential anticancer activity. DP-4978 displays activities against B-Raf or Ras mutant tumor cells. It binds to A-Raf; B-Raf and C-Raf isoforms with similar affinity in cells with activating mutations… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DP-4978, Biochemical
Full Product Name
DP-4978
Product Gene Name
DP-4978 biochemical
Product Synonym Names
1- (3; 3-dimethylbutyl)-3- (2-fluoro-4-methyl-5- (7-methyl-2- (methylamino) pyrido[2; 3-d]pyrimidin-6-yl) phenyl) urea; LY3009120
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
424.52
Salt Form
No
CAS Number
1454682-72-4 
Cell-Permeable
Yes
Reconstitution
DMSO
SMILES
CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F
InChi
InChI=1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,28,30)
InChi Key
HHCBMISMPSAZBF-UHFFFAOYSA-N

Structure of DP-4978 biochemical

DP-4978 1- (3 Biochemical – Cat# MBS846428

Other Notes

Small volumes of DP-4978 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DP-4978 purchase

MBS846428 is a biochemical targeting DP-4978.
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