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GSK-583

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846440

GSK-583 is a highly potent and selective Inhibitor of RIP2 Kinase (IC50 = 5 nM). RIP2 kinase is a central component of the innate immune system and enables downstream signaling following activation of the pattern recognition receptors NOD1 and NOD2; leading… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GSK-583, Biochemical
Full Product Name
GSK-583
Product Gene Name
GSK-583 biochemical
Product Synonym Names
6 (tert-Butylsulfonyl)N (5-fluoro1Hindazol-3-yl)quinolin-4-amine
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
398.46
Salt Form
No
Molecular Formula
C20H19FN4O2S
CAS Number
1346547-00-9 
Cell-Permeable
Yes
Reconstitution
DMSO (>10 mg/ml)
SMILES
CC(C)(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=NNC4=C3C=C(C=C4)F
InChi
InChI=1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)
InChi Key
XLOGLWKOHPIJLV-UHFFFAOYSA-N

Structure of GSK-583 biochemical

GSK-583 Biochemical – Cat# MBS846440

Other Notes

Small volumes of GSK-583 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-583 purchase

MBS846440 is a biochemical targeting GSK-583.
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