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Brivanib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846462

Brivanib is a potent; ATP-competitive inhibitor against human Flk-1 (VEGFR-2) and mouse Flk-1 with IC50 of 25 nM and 89 nM; respectively. Brivanib also inhibits VEGFR-1 and FGFR-1 with IC50 values of 0.38 and 0.148 muM. Brivanib displays antitumor… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Brivanib, Biochemical
Full Product Name
Brivanib
Product Synonym Names
(R)-1- ( (4- ( (4-fluoro-2-methyl-1H-indol-5-yl) oxy)-5-methylpyrrolo[2; 1-f][1; 2; 4]triazin-6-yl) oxy) propan-2-ol; BMS-540215
Form/Format
Crystalline solid
Purity/Purification
>=98% by HPLC
Preparation and Storage
Store at -20 degree C for 36 months.
Protect from air and light.
Molecular Weight
370.38
Salt Form
No
CAS Number
649735-46-6
Cell-Permeable
Yes
Reconstitution
DMSO (>30 mg/ml)
SMILES
CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OCC(C)O)C
InChi
InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1
InChi Key
WCWUXEGQKLTGDX-LLVKDONJSA-N

Structure of Brivanib biochemical

Brivanib Biochemical – Cat# MBS846462

Other Notes

Small volumes of Brivanib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Brivanib purchase

MBS846462 is a biochemical targeting Brivanib.
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