P7C3-A20 Modulator

P7C3-A20 is a neuroprotective and proneurogenic agent impacting NAMPT stimulation (1). It has been shown to display neuroprotection and promotes endogenous reparative functions after traumatic brain injury (TBI) (2). P7C3-A20 has been shown to repair the blood-brain barrier, arrests chronic neurodegeneration and restores cognition one year after TBI in a mouse model (3). In a hypoxic-ischemic encephalopathy model, P7C3-A20 displays neuroprotective qualities (4). In rat models, P7C3-A20 inhibits neuroinflammation and guards retinal ganglion cells from optic nerve crush (5).

Small volumes of P7C3-A20 modulator vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS556529 is a modulator targeting P7C3-A20.