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B7-H6 Human Cellexp Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846941

B7-H6 is a glycosylated member of the B7 family of immune costimulatory proteins. Orthologs in mouse and rat have not been identified. The Ig-like V domain mediates 1:1 stoichiometric binding of B7-H6 to NKp30 expressed on NK cells. It does not show binding… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
B7-H6, Recombinant Protein
Full Product Name
Human CellExp B7-H6; human recombinant
Product Gene Name
Product Synonym Gene Name
NCR3LG1
Product Synonym Names
Natural cytotoxicity triggering receptor 3 ligand 1
Host
HEK 293 cells
Source: Human
Form/Format
Lyophilized from 0.2 mum-filtered solution in PBS.
Purity/Purification
>= 98%
Preparation and Storage
Store at -20 degree C for 12 months.
Centrifuge the vial prior to opening.
Molecular Weight
80 kDa
OMIM
BX537685 mRNA
3D Structure
ModBase 3D Structure for Q68D85
Endotoxin Level
< 5 EU/mg
Reconstitution
Reconstitute in 1X PBS to the desired protein concentration.
Applications Tested/Suitable for B7-H6 recombinant protein
SDS-PAGE

Other Notes

Small volumes of B7-H6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for B7-H6 purchase

MBS846941 is a recombinant protein targeting B7-H6. Also known as Human CellExp B7-H6; human recombinant. Host: HEK 293 cells
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for B7-H6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
natural cytotoxicity triggering receptor 3 ligand 1
NCBI Official Synonym Full Names
natural killer cell cytotoxicity receptor 3 ligand 1
NCBI Official Symbol
NCR3LG1
NCBI Official Synonym Symbols
B7H6; B7-H6; DKFZp686O24166
UniProt Protein Name
Natural cytotoxicity triggering receptor 3 ligand 1
UniProt Synonym Protein Names
B7 homolog 6; B7-H6
UniProt Gene Name
NCR3LG1
UniProt Synonym Gene Names
B7H6; B7-H6
NCBI Protein Information
natural cytotoxicity triggering receptor 3 ligand 1

NCBI Summary for B7-H6

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]

UniProt Comments for B7-H6

B7-H6: Triggers NCR3-dependent natural killer cell activation.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: plasma membrane

Biological Process: regulation of immune response

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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