Human Cellexp NCAM1 Recombinant Protein – Cat# MBS846944

NCAM-1/CD56 (NCAM1) Human Cellexp Recombinant Protein

Name: NCAM1 Recombinant Protein; NCAM-1/CD56; Human Cellexp; MyBioSource
Brand: MyBioSource
SKU: MBS846944
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS846944

Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells in the immune system. It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and viruses. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

NCAM-1/CD56 (NCAM1), Recombinant Protein

Full Product Name

Human CellExp NCAM-1/CD56; human recombinant

Product Gene Name

NCAM1 recombinant protein

Product Synonym Gene Name

CD56

Product Synonym Names

NCAM; CD56; MSK39; NCAM1 neural cell adhesion molecule 1

Host

HEK 293 cells
Source: Human

Form/Format

Lyophilized from 0.2 mum-filtered solution in PBS.

Purity/Purification

>= 98%

Preparation and Storage

Store at -20 degree C for 12 months.
Centrifuge the vial prior to opening.

Molecular Weight

140 kDa

OMIM

X16841 mRNA

3D Structure

ModBase 3D Structure for P13591

Endotoxin Level

< 5 EU/mg

Reconstitution

Reconstitute in 1X PBS to the desired protein concentration.

Applications Tested/Suitable for NCAM1 recombinant protein

SDS-PAGE, Functional Assay

Other Notes

Small volumes of NCAM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NCAM1 purchase

MBS846944 is a recombinant protein targeting NCAM1. Also known as Human CellExp NCAM-1/CD56; human recombinant. Host: HEK 293 cells
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for NCAM1. It may not necessarily be applicable to this product.

NCBI GI #

94420689

NCBI GeneID

4684

NCBI Accession #

NP_000606.3

UniProt Primary Accession #

P13591

UniProt Secondary Accession #

P13592; P13593; Q05C58; Q15829; Q16180; Q16209; Q59FL7; Q86X47; Q96CJ3; A8K8T8

UniProt Related Accession #

P13591

GenBank Nucleotide #

NM_000615.6

NCBI Official Full Name

neural cell adhesion molecule 1 isoform 1

NCBI Official Synonym Full Names

neural cell adhesion molecule 1

NCBI Official Symbol

NCAM1

NCBI Official Synonym Symbols

CD56; NCAM; MSK39

UniProt Protein Name

Neural cell adhesion molecule 1

UniProt Synonym Protein Names

CD_antigen: CD56

Protein Family

Neural cell adhesion molecule

UniProt Gene Name

NCAM1

UniProt Synonym Gene Names

NCAM; N-CAM-1; NCAM-1

NCBI Protein Information

neural cell adhesion molecule 1

NCBI Summary for NCAM1

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

UniProt Comments for NCAM1

NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, GPI anchor; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: cell surface; cytosol; external side of plasma membrane; Golgi membrane; membrane; plasma membrane

Molecular Function: Ras guanyl-nucleotide exchange factor activity

Biological Process: axon guidance; MAPKKK cascade

Research Articles on NCAM1

1. Study provides detailed description of the PSA-NCAM distribution throughout the human brain and quantitatively compares control, Alzheimer's and Parkinson's disease. Results demonstrate that PSA-NCAM-mediated structural plasticity may not be limited to neurogenic niches and is conserved in the aged brain, provide evidence that PSA-NCAM is reduced in the entorhinal cortex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NCAM1 recombinant protein

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
Cardiac Progenitor Differentiation Pathway antibodies	Cardiac Progenitor Differentiation Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
ECM Proteoglycans Pathway antibodies	ECM Proteoglycans Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
FGF Signaling Pathway antibodies	FGF Signaling Pathway Diagram

Diseases associated with NCAM1 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>984 publications with NCAM1 and Nervous System Diseases
Brain Diseases Antibodies	>537 publications with NCAM1 and Brain Diseases
Necrosis Antibodies	>276 publications with NCAM1 and Necrosis
Disease Models, Animal Antibodies	>257 publications with NCAM1 and Disease Models, Animal
Inflammation Antibodies	>237 publications with NCAM1 and Inflammation
Lung Neoplasms Antibodies	>224 publications with NCAM1 and Lung Neoplasms
Cardiovascular Diseases Antibodies	>219 publications with NCAM1 and Cardiovascular Diseases
Congenital Abnormalities Antibodies	>195 publications with NCAM1 and Congenital Abnormalities
Liver Diseases Antibodies	>179 publications with NCAM1 and Liver Diseases
Neoplasm Invasiveness Antibodies	>146 publications with NCAM1 and Neoplasm Invasiveness

Organs/Tissues associated with NCAM1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2715 publications with NCAM1 and Brain
Blood Antibodies	>2492 publications with NCAM1 and Blood
Nerve Antibodies	>1729 publications with NCAM1 and Nerve
Embryonic Tissue Antibodies	>831 publications with NCAM1 and Embryonic Tissue
Muscle Antibodies	>564 publications with NCAM1 and Muscle
Bone Antibodies	>525 publications with NCAM1 and Bone
Skin Antibodies	>379 publications with NCAM1 and Skin
Vascular Antibodies	>365 publications with NCAM1 and Vascular
Eye Antibodies	>337 publications with NCAM1 and Eye
Lung Antibodies	>326 publications with NCAM1 and Lung