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Glyoxalase II (Glx II) (GLX II) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847000

The glyoxalase system consists of Glyoxalase I (Glx I) and Glyoxalase II (Glx II) which is responsible for detoxifying alpha-ketoaldehydes such as the potent and cytotoxic methylglyoxal (MG). Glx I converts MG to S-D-lactoyl-glutathione (SLG). SLG is then… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Glyoxalase II (Glx II), Active Protein
Full Product Name
Glyoxalase II (Glx II); Human Recombinant
Product Gene Name
Product Synonym Gene Name
HAGH
Product Synonym Names
Hydroxyacylglutathione hydrolase; mitochondrial; HAGH1; GLO2
Host
E Coli
Source: Human
Form/Format
Liquid
30% glycerol; 50 mM Tris pH 7.4 and 150 mM NaCl
Purity/Purification
>=90%
Preparation and Storage
Store at -20 degree C for 12 months.
Centrifuge the vial prior to opening.
Molecular Weight
32.4 kDa
OMIM
AK290155 mRNA
3D Structure
ModBase 3D Structure for Q16775
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
>= 10 U/mg, in which one unit is the amount of enzyme that will hydrolyze 1.0 umole of SLG per minute at pH 7.4 at 25 degree C.
Results
>= 10 U/mg
Unit Definition
One unit is the amount of enzyme that will hydrolyze 1.0 umole of SLG per minute at pH 7.4 at 25 degree C.
Applications Tested/Suitable for Glx II active protein
SDS-PAGE

Testing Data of Glx II active protein

GLX II Active Protein – Cat# MBS847000

Other Notes

Small volumes of Glx II active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Glx II purchase

MBS847000 is an active protein targeting Glx II. Also known as Glyoxalase II (Glx II); Human Recombinant. Host: E Coli
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for Glx II. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
hydroxyacylglutathione hydrolase, mitochondrial isoform 2
NCBI Official Synonym Full Names
hydroxyacylglutathione hydrolase
NCBI Official Symbol
HAGH
NCBI Official Synonym Symbols
GLO2; GLX2; GLXII; HAGH1
UniProt Protein Name
Hydroxyacylglutathione hydrolase, mitochondrial
UniProt Synonym Protein Names
Glyoxalase II; Glx II
UniProt Gene Name
HAGH
UniProt Synonym Gene Names
GLO2; HAGH1; Glx II
NCBI Protein Information
hydroxyacylglutathione hydrolase, mitochondrial

NCBI Summary for Glx II

The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

UniProt Comments for Glx II

Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Glx II active protein

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