Human Cellexp PD-1 Recombinant Protein – Cat# MBS847014

Pd-1/PDCD1 (PD-1) Human Cellexp Recombinant Protein

Name: PD-1 Recombinant Protein; Pd-1/PDCD1; Human Cellexp; MyBioSource
Brand: MyBioSource
SKU: MBS847014
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847014

Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1; is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells; B cells; macrophages;… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PD-1/PDCD1, Recombinant Protein

Full Product Name

Human CellExp PD-1/PDCD1 Protein; mouse recombinant

Product Gene Name

PD-1 recombinant protein

Product Synonym Gene Name

PDCD1

Product Synonym Names

PDCD1; PD1; CD279; SLEB2; hPD-1; hPD-l

Host

HEK 293 cells
Source: Mouse

Form/Format

Lyophilized from 0.22 mum filtered solution in PBS; pH 7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.

Purity/Purification

>=95%

Preparation and Storage

Store at -20 degree C for 12 months.
Centrifuge the vial prior to opening.

Molecular Weight

43.7 kDa

3D Structure

ModBase 3D Structure for Q02242

Endotoxin Level

< 1 EU/mug

Reconstitution

Reconstitute in sterile deionized water to a concentration of 50 mug/ml.

Applications Tested/Suitable for PD-1 recombinant protein

SDS-PAGE

Other Notes

Small volumes of PD-1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PD-1 purchase

MBS847014 is a recombinant protein targeting PD-1. Also known as Human CellExp PD-1/PDCD1 Protein; mouse recombinant. Host: HEK 293 cells
Source: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PD-1. It may not necessarily be applicable to this product.

NCBI GI #

6679239

NCBI GeneID

18566

NCBI Accession #

NP_032824.1

UniProt Primary Accession #

Q02242

UniProt Related Accession #

Q02242

GenBank Nucleotide #

NM_008798.2

NCBI Official Full Name

programmed cell death protein 1

NCBI Official Synonym Full Names

programmed cell death 1

NCBI Official Symbol

Pdcd1

NCBI Official Synonym Symbols

PD-1; Pdc1; Ly101

UniProt Protein Name

Programmed cell death protein 1

UniProt Synonym Protein Names

CD_antigen: CD279

Protein Family

Programmed cell death

UniProt Gene Name

Pdcd1

UniProt Synonym Gene Names

Pd1; Protein PD-1; mPD-1

NCBI Protein Information

programmed cell death protein 1

UniProt Comments for PD-1

PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1|1 D

Cellular Component: external side of plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of apoptosis; negative regulation of tolerance induction; positive regulation of apoptosis

Research Articles on PD-1

1. we provide evidence that indicates that the PD-1(+) fraction of DN T cells represents self-reactive cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PD-1 recombinant protein

Reference Product	PubMed Publications
Cd4 recombinant protein	>418 publications with PD-1 and Cd4
Cd274 recombinant protein	>336 publications with PD-1 and Cd274
Pdcd1lg2 recombinant protein	>99 publications with PD-1 and Pdcd1lg2
Ptpn6 recombinant protein	>7 publications with PD-1 and Ptpn6
Ptpn11 recombinant protein	>7 publications with PD-1 and Ptpn11
Lck recombinant protein	>3 publications with PD-1 and Lck
Cd247 recombinant protein	>1 publications with PD-1 and Cd247
Cd3e recombinant protein	>1 publications with PD-1 and Cd3e

Pathways associated with PD-1 recombinant protein

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Costimulation By The CD28 Family Pathway antibodies	Costimulation By The CD28 Family Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
PD-1 Signaling Pathway antibodies	PD-1 Signaling Pathway Diagram
T Cell Receptor Signaling Pathway antibodies	T Cell Receptor Signaling Pathway Diagram
T Cell Receptor Signaling Pathway antibodies	T Cell Receptor Signaling Pathway Diagram

Diseases associated with PD-1 recombinant protein

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>147 publications with PD-1 and Liver Diseases
Inflammation Antibodies	>115 publications with PD-1 and Inflammation
Melanoma Antibodies	>79 publications with PD-1 and Melanoma
Necrosis Antibodies	>75 publications with PD-1 and Necrosis
Lupus Erythematosus, Systemic Antibodies	>72 publications with PD-1 and Lupus Erythematosus, Systemic
Lung Diseases Antibodies	>58 publications with PD-1 and Lung Diseases
Lung Neoplasms Antibodies	>38 publications with PD-1 and Lung Neoplasms
Adenocarcinoma Antibodies	>35 publications with PD-1 and Adenocarcinoma
Kidney Diseases Antibodies	>28 publications with PD-1 and Kidney Diseases
Liver Neoplasms Antibodies	>26 publications with PD-1 and Liver Neoplasms

Organs/Tissues associated with PD-1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>23 publications with PD-1 and Thymus