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H2BK16ac Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847107

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core… More details

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Product Overview

Product Name
H2BK16ac, Polyclonal Antibody
Full Product Name
Anti-H2BK16ac Antibody
Product Gene Name
Product Synonym Names
Histone H2B type 1-B (Histone H2B.1) (Histone H2B.f) (H2B/f); HIST1H2BB; H2BFF
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Colorless liquid. In 0.01M PBS; pH7.4; 50% Glycerol; 0.03% proclin 300
Purity/Purification
Antigen Affinity purified
Specificity
Affinity purified rabbit polyclonal antibody to detect acetylation of Histone H2B at Lysine 16 in human samples
Preparation and Storage
Store at -20 degree C. The antibody solution should be gently mixed before use.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA
Molecular Weight
13,950 Da
OMIM
602803
3D Structure
ModBase 3D Structure for P33778
Antibody Target
H2BK16ac
Immunogen
Acetylated peptide sequence targeting residues around Lysine 16 of human Histone H2B type 1-B
Applications Tested/Suitable for anti-H2BK16ac antibody
Chromatin Immunoprecipitation (ChIP); Immunofluorescence (IF); Immunocytochemistry (ICC)
Application Notes for anti-H2BK16ac antibody
ICC: 1:20-1:200
IF: 1:50-1:200

Chromatin Immunoprecipitation (ChIP) of anti-H2BK16ac antibody

Rabbit Anti-H2BK16ac Polyclonal Antibody – Cat# MBS847107

Immunofluorescence (IF) of anti-H2BK16ac antibody

Rabbit Anti-H2BK16ac Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS847107

Immunohistochemistry (IHC) of anti-H2BK16ac antibody

Rabbit Anti-H2BK16ac Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS847107

Other Notes

Small volumes of anti-H2BK16ac antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for H2BK16ac purchase

MBS847107 is an antibody targeting H2BK16ac. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for H2BK16ac. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
histone H2B type 1-B
NCBI Official Synonym Full Names
histone cluster 1, H2bb
NCBI Official Symbol
HIST1H2BB
NCBI Official Synonym Symbols
H2B.1; H2B/f; H2BFF
UniProt Protein Name
Histone H2B type 1-B
UniProt Synonym Protein Names
Histone H2B.1; Histone H2B.f; H2B/f
UniProt Gene Name
HIST1H2BB
UniProt Synonym Gene Names
H2BFF; H2B/f
UniProt Entry Name
H2B1B_HUMAN
NCBI Protein Information
histone H2B type 1-B; H2B histone family, member F; histone 1, H2bb; histone H2B.1; histone H2B.f

NCBI Summary for H2BK16ac

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]
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UniProt Comments for H2BK16ac

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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