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IL-8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847129

The protein encoded by this gene is a member of the CXC chemokine family and is a major mediator of the inflammatory response. The encoded protein is secreted primarily by neutrophils, where it serves as a chemotactic factor by guiding the neutrophils to the… More details

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Product Overview

Product Name
IL-8, Polyclonal Antibody
Full Product Name
Anti-IL-8 Antibody
Product Gene Name
anti-IL-8 antibody
Product Synonym Names
Interleukin-8 (IL-8) (C-X-C motif chemokine 8) (Chemokine (C-X-C motif) ligand 8) (Emoctakin) (Granulocyte chemotactic protein 1) (GCP-1) (Monocyte-derived neutrophil chemotactic factor) (MDNCF) (Monocyte-derived neutrophil-activating peptide) (MONAP) (Neutrophil-activating protein 1) (NAP-1) (Protein 3-10C) (T-cell chemotactic factor) [Cleaved into: MDNCF-a (GCP/IL-8 protein IV) (IL8/NAP1 form I); Interleukin-8 ((Ala-IL-8)77) (GCP/IL-8 protein II) (IL-8(1-77)) (IL8/NAP1 form II) (MDNCF-b); IL-8(5-77); IL-8(6-77) ((Ser-IL-8)72) (GCP/IL-8 protein I) (IL8/NAP1 form III) (Lymphocyte-derived neutrophil-activating factor) (LYNAP) (MDNCF-c) (Neutrophil-activating factor) (NAF); IL-8(7-77) (GCP/IL-8 protein V) (IL8/NAP1 form IV); IL-8(8-77) (GCP/IL-8 protein VI) (IL8/NAP1 form V); IL-8(9-77) (GCP/IL-8 protein III) (IL8/NAP1 form VI)]; CXCL8; IL8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Colorless liquid. In 0.01M PBS; 50% glycerol; 0.03% proclin 300; pH7.4
Purity/Purification
Affinity purified
Specificity
Affinity purified rabbit polyclonal antibody to detect IL-8 expression in human samples
Preparation and Storage
Store at -20 degree C. The antibody solution should be gently mixed before use.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA
Molecular Weight
11kDa
Chromosome Location
Chromosome: 4; NC_000004.11 (74606223..74609433). Location: 4q13-q21
OMIM
146930
3D Structure
ModBase 3D Structure for P10145
Antibody Target
IL-8
Immunogen
Recombinant Human Interleukin-8 protein (23-99 aa)

Product Categories/Family for anti-IL-8 antibody

Web Categories; Cardiovascular Research; Angiogenesis; Antibodies; Cancer Research; Antibodies & Supporting Tools; Primary Antibodies (A-Z); Proteins and Enzymes; Cytokines; Growth Factors & Hormones; Antibodies to Cytokines & Growth Factors (A-Z); Primar
Applications Tested/Suitable for anti-IL-8 antibody
Immunohistochemistry (IHC); Western Blotting (WB)
Application Notes for anti-IL-8 antibody
WB: 1:1000-1:5000
IHC: 1:20-1:200

Immunohistochemistry (IHC) of anti-IL-8 antibody

Rabbit Anti-IL-8 Polyclonal Antibody – Cat# MBS847129

Western Blot (WB) of anti-IL-8 antibody

Rabbit Anti-IL-8 Polyclonal Antibody, Western Blot (WB) – Cat# MBS847129

Other Notes

Small volumes of anti-IL-8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-8 purchase

MBS847129 is an antibody targeting IL-8. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-8. It may not necessarily be applicable to this product.

NCBI GI #
10834978
NCBI GeneID
3576
NCBI Accession #
NP_000575.1
UniProt Primary Accession #
P10145
UniProt Secondary Accession #
Q6FGF6; Q6LAE6; Q96RG6; Q9C077; Q9UCE1; Q9UCR8; Q9UCR9; Q9UCS0; B2R4L8
UniProt Related Accession #
P10145
GenBank Nucleotide #
NM_000584.3
NCBI Official Full Name
interleukin-8
NCBI Official Synonym Full Names
interleukin 8
NCBI Official Symbol
IL8
NCBI Official Synonym Symbols
NAF; GCP1; LECT; LUCT; NAP1; CXCL8; GCP-1; LYNAP; MDNCF; MONAP; NAP-1
UniProt Protein Name
Interleukin-8
UniProt Synonym Protein Names
C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factorCleaved into the following 7 chains:MDNCF-a; Alternative name(s):; GCP/IL-8 protein IV; IL8/NAP1 form IInterleukin-8; Alternative name(s):; (Ala-IL-8)77; GCP/IL-8 protein II; IL-8(1-77); IL8/NAP1 form II; MDNCF-bIL-8(5-77)IL-8(6-77); Alternative name(s):; (Ser-IL-8)72; GCP/IL-8 protein I; IL8/NAP1 form III; Lymphocyte-derived neutrophil-activating factor; LYNAP; MDNCF-c; Neutrophil-activating factor; NAFIL-8(7-77); Alternative name(s):; GCP/IL-8 protein V; IL8/NAP1 form IVIL-8(8-77); Alternative name(s):; GCP/IL-8 protein VI; IL8/NAP1 form VIL-8(9-77); Alternative name(s):; GCP/IL-8 protein III; IL8/NAP1 form VI
UniProt Gene Name
IL8
UniProt Synonym Gene Names
CXCL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF
UniProt Entry Name
IL8_HUMAN
NCBI Protein Information
interleukin-8; emoctakin; T-cell chemotactic factor; neutrophil-activating peptide 1; chemokine (C-X-C motif) ligand 8; beta-thromboglobulin-like protein; granulocyte chemotactic protein 1; tumor necrosis factor-induced gene 1; alveolar macrophage chemota

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL-8 antibody

 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activation Of Genes By ATF4 Pathway antibodies  Activation Of Genes By ATF4 Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram

Diseases associated with anti-IL-8 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >675 publications with IL-8 and Inflammation
 Necrosis Antibodies  >395 publications with IL-8 and Necrosis
 Hypersensitivity Antibodies  >66 publications with IL-8 and Hypersensitivity
 Drug Toxicity Antibodies  >62 publications with IL-8 and Drug Toxicity
 Adenocarcinoma Antibodies  >49 publications with IL-8 and Adenocarcinoma
 Pulmonary Disease, Chronic Obstructive Antibodies  >48 publications with IL-8 and Pulmonary Disease, Chronic Obstructive
 Pneumonia Antibodies  >34 publications with IL-8 and Pneumonia
 Colorectal Neoplasms Antibodies  >30 publications with IL-8 and Colorectal Neoplasms
 Kidney Diseases Antibodies  >27 publications with IL-8 and Kidney Diseases
 Breast Neoplasms Antibodies  >26 publications with IL-8 and Breast Neoplasms

Organs/Tissues associated with anti-IL-8 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >669 publications with IL-8 and Blood
 Lung Antibodies  >237 publications with IL-8 and Lung
 Vascular Antibodies  >201 publications with IL-8 and Vascular
 Intestine Antibodies  >90 publications with IL-8 and Intestine
 Skin Antibodies  >81 publications with IL-8 and Skin
 Liver Antibodies  >71 publications with IL-8 and Liver
 Heart Antibodies  >67 publications with IL-8 and Heart
 Bone Antibodies  >60 publications with IL-8 and Bone
 Muscle Antibodies  >59 publications with IL-8 and Muscle
 Brain Antibodies  >48 publications with IL-8 and Brain
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