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GPT2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847144

Alanine aminotransferase 2 catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
GPT2/ALT2, Polyclonal Antibody
Full Product Name
Anti-GPT2/ALT2 Antibody
Product Gene Name
Product Synonym Names
AAT2; ALT2; Alanine aminotransferase 2; ALT2; Glutamate pyruvate transaminase 2; GPT 2; Glutamic-alanine transaminase 2; Glutamic--pyruvic transaminase 2
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Colorless liquid. In PBS pH7.3 containing 0.2% BSA and 0.02% sodium azide
Purity/Purification
Affinity purification. The antibody was purified by affinity chromatography
Specificity
Polyclonal antibody to detect endogenous levels of GPT2/ALT2 in human samples.
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use
Shelf life: ~12 months
Molecular Weight
523
OMIM
138210
3D Structure
ModBase 3D Structure for Q8TD30
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ALT2.
Positive Control
WB: SHSY5Y, HepG2, HEK293T whole cell lysates
Applications Tested/Suitable for anti-GPT2 antibody
Western Blot (WB)
Application Notes for anti-GPT2 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-GPT2 antibody

Rabbit Anti-GPT2 Polyclonal Antibody – Cat# MBS847144

Other Notes

Small volumes of anti-GPT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GPT2 purchase

MBS847144 is an antibody targeting GPT2. Also known as Anti-GPT2/ALT2 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GPT2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Alanine aminotransferase 2
NCBI Official Synonym Full Names
glutamic pyruvate transaminase (alanine aminotransferase) 2
NCBI Official Symbol
GPT2
NCBI Official Synonym Symbols
ALT2
UniProt Protein Name
Alanine aminotransferase 2
UniProt Synonym Protein Names
Glutamate pyruvate transaminase 2; GPT 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2
UniProt Gene Name
GPT2
UniProt Synonym Gene Names
AAT2; ALT2; ALT2; GPT 2
UniProt Entry Name
ALAT2_HUMAN
NCBI Protein Information
alanine aminotransferase 2; GPT 2; glutamic--alanine transaminase 2; glutamic--pyruvic transaminase 2; glutamic-pyruvate transaminase 2; glutamate pyruvate transaminase 2

NCBI Summary for GPT2

This gene encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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UniProt Comments for GPT2

GPT2: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; EC 2.6.1.2; Amino Acid Metabolism - alanine, aspartate and glutamate; Transferase

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: mitochondrial matrix

Molecular Function: alanine transaminase activity; pyridoxal phosphate binding

Biological Process: amino acid biosynthetic process; L-alanine metabolic process; 2-oxoglutarate metabolic process; L-alanine catabolic process

Disease: Mental Retardation, Autosomal Recessive 49
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GPT2 antibody

 Reference Product  PubMed Publications
 LDHB antibody  >1 publications with GPT2 and LDHB
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