NAMPT Antibody – Mouse Monoclonal

PBEF: an ubiquitous protein originally described as a cytokine which acts on early B-lineage precursor cells. Other reports indicate that PBEF is not a cytokine-like secreted protein but an intracellular protein associated with the cell cycle. Contains a catalytically active nicotinate phosphoribosyltransferase domain, an enzyme involved in nicotinamide adenine dinucleotide (NAD) biosynthesis.

Protein type: Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Cell cycle regulation; Cytokine; Transferase; EC 2.4.2.12

Cellular Component: extracellular space; cytoplasm; extracellular region; nucleus

Molecular Function: transferase activity; transferase activity, transferring glycosyl groups; protein homodimerization activity; cytokine activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; drug binding; nicotinamide phosphoribosyltransferase activity

Biological Process: NAD biosynthetic process; positive regulation of smooth muscle cell proliferation; rhythmic process; pyridine nucleotide biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; positive regulation of nitric-oxide synthase biosynthetic process