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ARL2BP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847274

Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 More details

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Product Overview

Product Name
ARL2BP, Polyclonal Antibody
Full Product Name
Anti-ARL2BP Antibody
Product Gene Name
Product Synonym Names
BART; BART1; ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; ARL2-binding protein; Binder of ARF2 protein 1
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH7.3; 30% glycerol and 0.01% sodium azide
Purity/Purification
Affinity purification. The antibody was purified by affinity chromatography
Specificity
Polyclonal Antibody to detect ARL2BP in human, mouse and rat samples
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
18,822 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (57279038..57287545). Location: 16q13
3D Structure
ModBase 3D Structure for Q9Y2Y0
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ARL2BP
Positive Control
WB: 1:500 - 1:2000
Applications Tested/Suitable for anti-ARL2BP antibody
Western Blot (WB)

Western Blot (WB) of anti-ARL2BP antibody

Rabbit Anti-ARL2BP Polyclonal Antibody – Cat# MBS847274

Other Notes

Small volumes of anti-ARL2BP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARL2BP purchase

MBS847274 is an antibody targeting ARL2BP. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARL2BP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ADP-ribosylation factor-like protein 2-binding protein
NCBI Official Synonym Full Names
ADP-ribosylation factor-like 2 binding protein
NCBI Official Symbol
ARL2BP
NCBI Official Synonym Symbols
BART; BART1
UniProt Protein Name
ADP-ribosylation factor-like protein 2-binding protein
UniProt Synonym Protein Names
Binder of ARF2 protein 1
UniProt Gene Name
ARL2BP
UniProt Synonym Gene Names
BART; BART1; ARF-like 2-binding protein
UniProt Entry Name
AR2BP_HUMAN
NCBI Protein Information
ADP-ribosylation factor-like protein 2-binding protein; binder of Arl2; binder of Arl Two; binder of ARF2 protein 1; ARF-like 2-binding protein; Arf-like 2 binding protein BART1

NCBI Summary for ARL2BP

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
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UniProt Comments for ARL2BP

ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Mitochondrial

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: centrosome; mitochondrial intermembrane space; spindle; midbody; nucleus; cilium

Molecular Function: protein binding; transcription coactivator activity

Biological Process: regulation of catalytic activity; maintenance of protein localization in nucleus; signal transduction; positive regulation of tyrosine phosphorylation of Stat3 protein

Disease: Retinitis Pigmentosa With Or Without Situs Inversus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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