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AGPAT3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847275

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or… More details

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Product Overview

Product Name
AGPAT3, Polyclonal Antibody
Full Product Name
Anti-AGPAT3 Antibody
Product Gene Name
anti-AGPAT3 antibody
Product Synonym Names
LPAAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-AGP acyltransferase 3; 1-AGPAT 3; Lysophosphatidic acid acyltransferase gamma; LPAAT-gamma
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH7.3; 30% glycerol and 0.01% sodium azide
Purity/Purification
Affinity purification. The antibody was purified by affinity chromatography
Specificity
Polyclonal Antibody to detect endogenous levels of AGPAT3 in human, mouse and rat samples
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
43,381 Da
Chromosome Location
Chromosome: 21; NC_000021.8 (45285116..45407475). Location: 21q22.3
OMIM
614794
3D Structure
ModBase 3D Structure for Q9NRZ7
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LPAAT gamma
Positive Control
WB: K562; A549; PC12; mouse testis; rat testis whole cell lysates

Product Categories/Family for anti-AGPAT3 antibody

Signal Transduction; Signaling Pathways; AMPK; Insulin; Leptin Signaling Antibodies
Applications Tested/Suitable for anti-AGPAT3 antibody
Western Blot (WB)
Application Notes for anti-AGPAT3 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-AGPAT3 antibody

Rabbit Anti-AGPAT3 Polyclonal Antibody – Cat# MBS847275

Other Notes

Small volumes of anti-AGPAT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGPAT3 purchase

MBS847275 is an antibody targeting AGPAT3. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AGPAT3. It may not necessarily be applicable to this product.

NCBI GI #
83267874
NCBI GeneID
56894
NCBI Accession #
NP_001032642.1
UniProt Primary Accession #
Q9NRZ7
UniProt Secondary Accession #
Q3ZCU2; Q6UWP6; Q6ZUC6; Q8N3Q7; Q9NRZ6; D3DSL2
UniProt Related Accession #
Q9NRZ7
GenBank Nucleotide #
NM_001037553.1
NCBI Official Full Name
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
NCBI Official Synonym Full Names
1-acylglycerol-3-phosphate O-acyltransferase 3
NCBI Official Symbol
AGPAT3
NCBI Official Synonym Symbols
LPAAT3; LPAAT-GAMMA1
UniProt Protein Name
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
UniProt Synonym Protein Names
1-acylglycerol-3-phosphate O-acyltransferase 3; 1-AGP acyltransferase 3; 1-AGPAT 3; Lysophosphatidic acid acyltransferase gamma
Protein Family
1-acyl-sn-glycerol-3-phosphate acyltransferase
UniProt Gene Name
AGPAT3
UniProt Synonym Gene Names
LPAAT3; 1-AGP acyltransferase 3; 1-AGPAT 3; LPAAT-gamma
UniProt Entry Name
PLCC_HUMAN
NCBI Protein Information
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; 1-AGPAT 3; 1-AGP acyltransferase 3; lysophosphatidic acid acyltransferase gamma; lysophosphatidic acid acyltransferase-gamma1

NCBI Summary for AGPAT3

The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for AGPAT3

AGPAT3: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - ether lipid; Membrane protein, multi-pass; Acetyltransferase; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; EC 2.3.1.51

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane; plasma membrane; nuclear envelope

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity

Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; CDP-diacylglycerol biosynthetic process; phospholipid biosynthetic process
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Research Articles on AGPAT3

1. enzymatic properties, tissue distribution, and subcellular localization of human AGPAT3 and AGPAT5

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AGPAT3 antibody

 Products by Pathway  Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram

Organs/Tissues associated with anti-AGPAT3 antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >3 publications with AGPAT3 and Heart
 Muscle Antibodies  >2 publications with AGPAT3 and Muscle
 Ovary Antibodies  >1 publications with AGPAT3 and Ovary
 Testis Antibodies  >1 publications with AGPAT3 and Testis
 Brain Antibodies  >1 publications with AGPAT3 and Brain
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