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MLK4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847282

Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MLK4, Polyclonal Antibody
Full Product Name
Anti-MLK4 Antibody
Product Gene Name
Product Synonym Names
KIAA1804; Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4; MLK4
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH7.3; 30% glycerol and 0.01% sodium azide
Purity/Purification
Affinity purification. The antibody was purified by affinity chromatography
Specificity
Polyclonal Antibody to detect endogenous levels of MLK4 in human samples
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
113,957 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (233463514..233520894). Location: 1q42
OMIM
614793
3D Structure
ModBase 3D Structure for Q5TCX8
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MLK4
Positive Control
WB: HT29; Hela cell lysate
Applications Tested/Suitable for anti-MLK4 antibody
Western Blot (WB)
Application Notes for anti-MLK4 antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-MLK4 antibody

Rabbit Anti-MLK4 Polyclonal Antibody – Cat# MBS847282

Other Notes

Small volumes of anti-MLK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLK4 purchase

MBS847282 is an antibody targeting MLK4. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MLK4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase MLK4
NCBI Official Symbol
KIAA1804
NCBI Official Synonym Symbols
MLK4; dJ862P8.3; RP5-862P8.2
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase MLK4
UniProt Synonym Protein Names
Mixed lineage kinase 4
UniProt Gene Name
MLK4
UniProt Synonym Gene Names
KIAA1804
UniProt Entry Name
M3KL4_HUMAN
NCBI Protein Information
mitogen-activated protein kinase kinase kinase MLK4

UniProt Comments for MLK4

MLK4: Activates the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Protein kinase, TKL; Kinase, protein; EC 2.7.11.25; Protein kinase, Ser/Thr (non-receptor); TKL group; MLK family; MLK subfamily

Chromosomal Location of Human Ortholog: 1q42

Molecular Function: protein homodimerization activity; MAP kinase kinase kinase activity; protein-tyrosine kinase activity; ATP binding

Biological Process: peptidyl-tyrosine phosphorylation; activation of MAPKK activity; protein amino acid autophosphorylation; protein amino acid phosphorylation; activation of JNK activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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