Human Anti-RSV Monoclonal Antibody – Cat# MBS847318

IgG1 (RSV) Antibody – Human Monoclonal

Name: RSV Antibody; Monoclonal; Human; Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS847318
Price: 810 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847318

Recombinant monoclonal antibody to RSV. Manufactured using Recombinant Platform with variable regions (i.e. specificity) from the hybridoma RSHZ19 (Felvizumab). This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

RSV, IgG1, Monoclonal Antibody

Full Product Name

Anti-RSV (Felvizumab), Human IgG1 Antibody

Product Gene Name

anti-RSV antibody

Product Synonym Names

Human Respiratory Syncytical Virus; HRSV; Human respiratory syncytial virus Fusion Protein; HRSV F

Clonality

Monoclonal

Isotype

Human IgG1, kappa

Clone Number

RSHZ19

Host

Human

Species Reactivity

Respiratory Syncytial Virus

Form/Format

Colorless liquid. In PBS only

Purity/Purification

Affinity purified using Protein A

Specificity

Monoclonal antibody to detect RSV. This antibody is specific for the conserved fusion (F) protein of RSV.

Preparation and Storage

Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

Molecular Weight

50.1 kDa

3D Structure

ModBase 3D Structure for O36634

Antibody Type

Recombinant Antibody

Immunogen

This antibody was prepared by the humanization of an F protein-specific murine MAb, RSV19. More specifically, molecular techniques were used to insert the complementarity determining regions from murine RSV19 into a human IgG1 heavy and k light chain-variable domain framework.

Product Categories/Family for anti-RSV antibody

Immunology; Antibodies & Supporting Tools; Research Grade Biosimilar Antibodies

Other Notes

Small volumes of anti-RSV antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RSV purchase

MBS847318 is an antibody targeting RSV. Also known as Anti-RSV (Felvizumab), Human IgG1 Antibody. Reactive in Respiratory Syncytial Virus. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for RSV. It may not necessarily be applicable to this product.

NCBI GI #

9629206

NCBI GeneID

1489825

NCBI Accession #

NP_056863.1

UniProt Primary Accession #

O36634

GenBank Nucleotide #

NC_001781.1

NCBI Official Full Name

fusion protein

NCBI Official Symbol

UniProt Protein Name

Fusion glycoprotein F0

UniProt Gene Name

UniProt Synonym Gene Names

Protein F

UniProt Entry Name

FUS_HRSVB

NCBI Protein Information

UniProt Comments for RSV

During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participates in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.

Research Articles on RSV

1. Prefusion RSV F induced a larger quantity and higher quality of RSV-neutralizing serum antibodies and was highly protective

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.