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CHRDL1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847478

Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by… More details

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Product Overview

Product Name
CHRDL1, Monoclonal Antibody
Full Product Name
Anti-CHRDL1 Antibody (3H1-F6-A10)
Product Gene Name
Product Synonym Names
Chordin-like protein 1; Neuralin-1; Neurogenesin-1; Ventroptin; NRLN1
Clonality
Monoclonal
Isotype
Mouse IgG
Clone Number
3H1-F6-A10
Host
Mouse
Species Reactivity
Human
Form/Format
Colorless liquid. In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Purity/Purification
Affinity purification. The antibody was affinity-purified from rabbit serum by affinity-chromatography using epitope-specific immunogen.
Concentration
1mg/ml (lot specific)
Specificity
Monoclonal antibody to detect endogenous levels of endogenous levels of CHRDL1 in human samples. Does not cross-react with related proteins.
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~30 months
Molecular Weight
52,026 Da
OMIM
AY608914 mRNA
3D Structure
ModBase 3D Structure for Q9BU40
Immunogen
Purified recombinant human CHRDL1 protein fragments expressed in E Coli
Positive Control
WB: Human eye and HeLa cell lysate, IF/ICC: HeLa cells
Applications Tested/Suitable for anti-CHRDL1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CHRDL1 antibody
WB: 1:500-1:2000
ELISA: 1:10,000-20,000

Immunocytochemistry/Immunofluorescence (ICC/IF)) of anti-CHRDL1 antibody

Mouse Anti-CHRDL1 Monoclonal Antibody – Cat# MBS847478

Other Notes

Small volumes of anti-CHRDL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHRDL1 purchase

MBS847478 is an antibody targeting CHRDL1. Also known as Anti-CHRDL1 Antibody (3H1-F6-A10). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CHRDL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chordin-like protein 1 isoform 1
NCBI Official Synonym Full Names
chordin like 1
NCBI Official Symbol
CHRDL1
NCBI Official Synonym Symbols
CHL; MGC1; MGCN; VOPT; NRLN1; dA141H5.1
UniProt Protein Name
Chordin-like protein 1
UniProt Synonym Protein Names
Neuralin-1; Neurogenesin-1; Ventroptin
Protein Family
UniProt Gene Name
CHRDL1
UniProt Synonym Gene Names
NRLN1
NCBI Protein Information
chordin-like protein 1

NCBI Summary for CHRDL1

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
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UniProt Comments for CHRDL1

Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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