Rabbit Anti-CSPG5 Polyclonal Antibody – Cat# MBS847502

Neuroglycan C (CSPG5) Antibody – Rabbit Polyclonal

Name: CSPG5 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS847502
Price: 430 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847502

May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Neuroglycan C (CSPG5), Polyclonal Antibody

Full Product Name

Anti-Neuroglycan C Antibody

Product Gene Name

anti-CSPG5 antibody

Product Synonym Names

CALEB; NGC; Chondroitin sulfate proteoglycan 5; Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C; Neuroglycan C

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Colorless liquid. In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH7.3; 30% glycerol and 0.01% sodium azide

Purity/Purification

Affinity purification. The antibody was purified by affinity chromatography

Concentration

1mg/ml (lot specific)

Specificity

Polyclonal antibody to detect endogenous levels of Neuroglycan C in human, mouse and rat samples

Preparation and Storage

Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

Molecular Weight

60,016 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (47603728..47621730, complement). Location: 3p21.3

OMIM

606775

3D Structure

ModBase 3D Structure for O95196

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Neuroglycan C

Positive Control

WB: THP1; Raw264.7 whole cell lysates.

Product Categories/Family for anti-CSPG5 antibody

Stem Cells; Neuroscience Antibodies

Applications Tested/Suitable for anti-CSPG5 antibody

Western Blot (WB)

Application Notes for anti-CSPG5 antibody

WB: 1:500-1:1000

Other Notes

Small volumes of anti-CSPG5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSPG5 purchase

MBS847502 is an antibody targeting CSPG5. Also known as Anti-Neuroglycan C Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CSPG5. It may not necessarily be applicable to this product.

NCBI GI #

332635065

NCBI GeneID

10675

NCBI Accession #

NP_001193872.1

UniProt Primary Accession #

O95196

UniProt Secondary Accession #

Q71M39; Q71M40

UniProt Related Accession #

O95196

GenBank Nucleotide #

NM_001206943.1

NCBI Official Full Name

chondroitin sulfate proteoglycan 5 isoform 3

NCBI Official Synonym Full Names

chondroitin sulfate proteoglycan 5 (neuroglycan C)

NCBI Official Symbol

CSPG5

NCBI Official Synonym Symbols

NGC

UniProt Protein Name

Chondroitin sulfate proteoglycan 5

UniProt Synonym Protein Names

Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C

Protein Family

Chondroitin sulfate proteoglycan

UniProt Gene Name

CSPG5

UniProt Synonym Gene Names

CALEB; NGC

UniProt Entry Name

CSPG5_HUMAN

NCBI Protein Information

chondroitin sulfate proteoglycan 5; acidic leucine-rich EGF-like domain-containing brain protein

NCBI Summary for CSPG5

The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

UniProt Comments for CSPG5

CSPG5: May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: Golgi apparatus; lysosomal lumen; endoplasmic reticulum membrane; membrane; Golgi lumen; integral to plasma membrane; extracellular region; integral to membrane

Molecular Function: protein binding; growth factor activity

Biological Process: chondroitin sulfate metabolic process; regulation of synaptic transmission; nervous system development; chondroitin sulfate biosynthetic process; intracellular transport; glycosaminoglycan metabolic process; axon regeneration; regulation of growth; carbohydrate metabolic process; chondroitin sulfate catabolic process; pathogenesis; dermatan sulfate biosynthetic process

Research Articles on CSPG5

1. results suggest that NGC may be a novel candidate gene, and neuregulin signaling pathways may play an important role in schizophrenia

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CSPG5 antibody

Reference Product	PubMed Publications
GOPC antibody	>1 publications with CSPG5 and GOPC

Pathways associated with anti-CSPG5 antibody

Products by Pathway	Pathway Diagram
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway antibodies	A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway Diagram
CS/DS Degradation Pathway antibodies	CS/DS Degradation Pathway Diagram
Chondroitin Sulfate Biosynthesis Pathway antibodies	Chondroitin Sulfate Biosynthesis Pathway Diagram
Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies	Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
Dermatan Sulfate Biosynthesis Pathway antibodies	Dermatan Sulfate Biosynthesis Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway antibodies	Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway Diagram
MPS I - Hurler Syndrome Pathway antibodies	MPS I - Hurler Syndrome Pathway Diagram
MPS II - Hunter Syndrome Pathway antibodies	MPS II - Hunter Syndrome Pathway Diagram

Diseases associated with anti-CSPG5 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3 publications with CSPG5 and Nervous System Diseases
Disease Models, Animal Antibodies	>2 publications with CSPG5 and Disease Models, Animal
Learning Disorders Antibodies	>1 publications with CSPG5 and Learning Disorders
Neurobehavioral Manifestations Antibodies	>1 publications with CSPG5 and Neurobehavioral Manifestations
Cardiovascular Diseases Antibodies	>1 publications with CSPG5 and Cardiovascular Diseases

Organs/Tissues associated with anti-CSPG5 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>18 publications with CSPG5 and Brain
Eye Antibodies	>4 publications with CSPG5 and Eye
Embryonic Tissue Antibodies	>1 publications with CSPG5 and Embryonic Tissue