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SOX12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847516

MBS847516 is an antibody targeting SOX12. Reactive in Human, Mouse. Host: Rabbit. Binds to the sequence 5'-AACAAT-3' More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
SOX12, Polyclonal Antibody
Full Product Name
Anti-SOX12 Antibody
Product Gene Name
Product Synonym Names
Transcription factor SOX-12; Protein SOX-22; SOX12; SOX22
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Colorless liquid. In phosphate buffered saline, pH7.4, 150mM, NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity purification
Concentration
1mg/ml (lot specific)
Specificity
Polyclonal antibody to detect endogenous levels of SOX12 in human and mouse samples
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
34,122 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (306215..310872). Location: 20p13
OMIM
601947
3D Structure
ModBase 3D Structure for O15370
Immunogen
A synthesized peptide derived from human SOX12
Positive Control
WB: COLO205, Mouse myeloma cell lysates
Applications Tested/Suitable for anti-SOX12 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SOX12 antibody
WB: 1:1000-3000
ELISA (peptide): 1:20,000-1:40,000

Western Blot (WB) of anti-SOX12 antibody

Rabbit Anti-SOX12 Polyclonal Antibody – Cat# MBS847516

Other Notes

Small volumes of anti-SOX12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SOX12 protein
NCBI Official Synonym Full Names
SRY (sex determining region Y)-box 12
NCBI Official Symbol
SOX12
NCBI Official Synonym Symbols
SOX22
UniProt Protein Name
Transcription factor SOX-12
UniProt Synonym Protein Names
Protein SOX-22
Protein Family
UniProt Gene Name
SOX12
UniProt Synonym Gene Names
SOX22
UniProt Entry Name
SOX12_HUMAN
NCBI Protein Information
transcription factor SOX-12; SOX-22 protein; SRY-related HMG-box gene 22

NCBI Summary for SOX12

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]
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UniProt Comments for SOX12

Function: Binds to the sequence 5'-AACAAT-3'

By similarity.

Subcellular location: Nucleus Ref.1.

Tissue specificity: Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. Ref.1

Sequence similarities: Contains 1 HMG box DNA-binding domain.

Sequence caution: The sequence AAB69627.1 differs from that shown. Reason: Frameshift at positions 135 and 201.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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