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HOXB8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847533

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. More details

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Product Overview

Product Name
HOXB8, Polyclonal Antibody
Full Product Name
Anti-HOXB8 Antibody
Product Gene Name
Product Synonym Names
Homeobox B8; Homeobox protein Hox B8; Homeobox protein Hox-2.4; Homeobox protein Hox-2D; Homeobox protein Hox-B8; Homeobox protein HoxB8; HOX 2; Hox 2.4; HOX 2D; HOX B8; HOX2; Hox2.4; HOX2D; Hoxb8; HXB8_HUMAN
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Rat, Mouse, Human
Form/Format
Liquid. In PBS, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity purification
Concentration
1mg/ml (lot specific)
Specificity
Polyclonal antibody to detect endogenous levels of HOXB8 in human, mouse and rat sample
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
27,574 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (46689708..46692474, complement). Location: 17q21.3
OMIM
142963
3D Structure
ModBase 3D Structure for P17481
Immunogen
A synthesized peptide derived from human HOXB8
Positive Control
LOVO whole cell lysate
Applications Tested/Suitable for anti-HOXB8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-HOXB8 antibody
ELISA (peptide): 1:20,000-1:40,000
WB: 1:1000-3000

Western Blot (WB) of anti-HOXB8 antibody

Rabbit Anti-HOXB8 Polyclonal Antibody – Cat# MBS847533

Other Notes

Small volumes of anti-HOXB8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOXB8 purchase

MBS847533 is an antibody targeting HOXB8. Reactive in Rat, Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXB8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein Hox-B8
NCBI Official Synonym Full Names
homeobox B8
NCBI Official Symbol
HOXB8
NCBI Official Synonym Symbols
HOX2; HOX2D; Hox-2.4
UniProt Protein Name
Homeobox protein Hox-B8
UniProt Synonym Protein Names
Homeobox protein Hox-2.4; Homeobox protein Hox-2D
Protein Family
UniProt Gene Name
HOXB8
UniProt Synonym Gene Names
HOX2D
UniProt Entry Name
HXB8_HUMAN
NCBI Protein Information
homeobox protein Hox-B8; homeo box 2D; homeo box B8; homeobox protein Hox-2D; homeobox protein Hox-2.4

NCBI Summary for HOXB8

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008]
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UniProt Comments for HOXB8

HOXB8: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding; transcription factor activity

Biological Process: grooming behavior; anterior/posterior pattern formation; dorsal spinal cord development; negative regulation of myeloid cell differentiation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; adult locomotory behavior; sensory perception of pain; embryonic skeletal morphogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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