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Phospho-HBP1 (HBP1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847585

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by… More details

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Product Overview

Product Name
Phospho-HBP1, Polyclonal Antibody
Full Product Name
Phospho-HBP1 (Ser402) Antibody
Product Gene Name
Product Synonym Names
HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1; HBP1
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Colorless liquid. In phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Purity/Purification
Affinity purification
Concentration
1mg/ml (lot specific)
Specificity
Polyclonal antibody to detect Phospho-HBP1 (Ser402)
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
57,645 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (106809406..106842974). Location: 7q22-q31
3D Structure
ModBase 3D Structure for O60381
Immunogen
A synthesized peptide derived from human HBP1 around the phosphorylation site of Sersine 402
Applications Tested/Suitable for anti-HBP1 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB), ELISA (EIA)
Application Notes for anti-HBP1 antibody
WB: 1:500-1:2000
IF: 1:100-1:500
ICC: 1:100-1:500
ELISA (peptide): 1:20,000-1:40,000

ELISA (EIA) of anti-HBP1 antibody

Rabbit Anti-HBP1 Polyclonal Antibody – Cat# MBS847585

Immunocytochemistry/Immunofluorescence (ICC/IF)) of anti-HBP1 antibody

Rabbit Anti-HBP1 Polyclonal Antibody, Immunocytochemistry/Immunofluorescence (ICC/IF)) – Cat# MBS847585

Western Blot (WB) of anti-HBP1 antibody

Rabbit Anti-HBP1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS847585

Other Notes

Small volumes of anti-HBP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HBP1 purchase

MBS847585 is an antibody targeting HBP1. Also known as Phospho-HBP1 (Ser402) Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HBP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
HMG box-containing protein 1 isoform 1
NCBI Official Synonym Full Names
HMG-box transcription factor 1
NCBI Official Symbol
HBP1
UniProt Protein Name
HMG box-containing protein 1
UniProt Synonym Protein Names
HMG box transcription factor 1; High mobility group box transcription factor 1
UniProt Gene Name
HBP1
UniProt Entry Name
HBP1_HUMAN
NCBI Protein Information
HMG box-containing protein 1; HMG box transcription factor 1; high mobility group box transcription factor 1

UniProt Comments for HBP1

HBP1: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7q22.3

Cellular Component: nucleoplasm

Molecular Function: protein binding; DNA binding; RNA binding

Biological Process: Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of potassium ion transport; cell cycle arrest
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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