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IgA (Alpha1 & Alpha2) (IGHA1) Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847649

MBS847649 is an antibody targeting IGHA1. Also known as Anti-Human IgA (alpha1 & alpha2) Rabbit Monoclonal Antibody. Reactive in Human. Host: Rabbit. Rabbit monoclonal to Human IgA (alpha1& alpha2) More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IgA (alpha1 & alpha2) (IGHA1), Monoclonal Antibody
Full Product Name
Anti-Human IgA (alpha1 & alpha2) Rabbit Monoclonal Antibody
Product Gene Name
Product Synonym Names
IgA (alpha1& alpha2)
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
RM128
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purity/Purification
Protein A affinity purified from an animal origin-free culture supernatant.
Concentration
1.0mg/ml (lot specific)
Specificity
Affinity purified rabbit monoclonal to human IgA. Clone RM128 reacts to human IgA, including both IgA1 and IgA2. No cross reactivity with human IgG, IgM, IgD, or IgE.
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
160,000
Chromosome Location
Chromosome: 14; NC_000014.8 (106173505..106175001, complement). Location: 14q32.33
OMIM
146900
3D Structure
ModBase 3D Structure for P01876
Immunogen
Human IgA
Applications Tested/Suitable for anti-IGHA1 antibody
Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes for anti-IGHA1 antibody
ICC: 0.5ug/ml-2ug/ml
ELISA: 50 ng/well-200 ng/well (for Capture), 0.05ug/mL-0.2ug/mL (for Detection)
IHC: 0.1ug/ml-1ug/ml

ELISA (EIA) of anti-IGHA1 antibody

Rabbit Anti-IGHA1 Monoclonal Antibody – Cat# MBS847649

ELISA (EIA) of anti-IGHA1 antibody

Rabbit Anti-IGHA1 Monoclonal Antibody, ELISA (EIA) – Cat# MBS847649

ELISA (EIA) of anti-IGHA1 antibody

Rabbit Anti-IGHA1 Monoclonal Antibody, ELISA (EIA) – Cat# MBS847649

Immunohistochemistry (IHC) of anti-IGHA1 antibody

Rabbit Anti-IGHA1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS847649

Other Notes

Small volumes of anti-IGHA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGHA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Ig alpha-1 chain C region
NCBI Official Synonym Full Names
immunoglobulin heavy constant alpha 1
NCBI Official Symbol
IGHA1
NCBI Official Synonym Symbols
IgA1
UniProt Protein Name
Ig alpha-1 chain C region
UniProt Gene Name
IGHA1
UniProt Entry Name
IGHA1_HUMAN

UniProt Comments for IGHA1

IGHA1: Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.

Protein type: Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: retinal homeostasis; receptor-mediated endocytosis; glomerular filtration; antibacterial humoral response; immune response; protein-chromophore linkage
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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