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SEL1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847727

The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent… More details

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Sample Manual Insert View PDF
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Product Overview

Product Name
SEL1L, Polyclonal Antibody
Full Product Name
Anti-SEL1L Antibody
Product Gene Name
Product Synonym Names
PRO1063; SEL1L1; SEL1L; SEL1-LIKE; protein sel-1 homolog 1
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Rat, Mouse, Human
Form/Format
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Affinity purification
Specificity
Affinity purified rabbit polyclonal to SEL1L
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
33,530 Da
OMIM
602329
3D Structure
ModBase 3D Structure for Q9UBV2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-190 of human SEL1L
Applications Tested/Suitable for anti-SEL1L antibody
Western Blot (WB)
Application Notes for anti-SEL1L antibody
WB: 1:500-1:2000

Western Blot (WB) of anti-SEL1L antibody

Rabbit Anti-SEL1L Polyclonal Antibody – Cat# MBS847727

Other Notes

Small volumes of anti-SEL1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEL1L purchase

MBS847727 is an antibody targeting SEL1L. Reactive in Rat, Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEL1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein sel-1 homolog 1 isoform 1
NCBI Official Synonym Full Names
SEL1L ERAD E3 ligase adaptor subunit
NCBI Official Symbol
SEL1L
NCBI Official Synonym Symbols
SEL1L1; PRO1063; SEL1-LIKE
UniProt Protein Name
Protein sel-1 homolog 1
UniProt Synonym Protein Names
Suppressor of lin-12-like protein 1; Sel-1L
Protein Family
UniProt Gene Name
SEL1L
UniProt Synonym Gene Names
TSA305; UNQ128/PRO1063; Sel-1L
UniProt Entry Name
SE1L1_HUMAN
NCBI Protein Information
protein sel-1 homolog 1

UniProt Comments for SEL1L

SEL1L: May play a role in Notch signaling. May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Belongs to the sel-1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q31

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein binding

Biological Process: Notch signaling pathway; ER-associated protein catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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