Rabbit Anti-SIM2 Polyclonal Antibody – Cat# MBS847753

SIM2 Antibody – Rabbit Polyclonal

Name: SIM2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS847753
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847753

This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SIM2, Polyclonal Antibody

Full Product Name

Anti-SIM2 Antibody

Product Gene Name

anti-SIM2 antibody

Product Synonym Names

HMC13F06; HMC29C01; SIM2; single-minded homolog 2; bHLHe15; SIM

Clonality

Polyclonal

Isotype

Rabbit IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purity/Purification

Affinity purification

Specificity

Affinity purified rabbit polyclonal to SIM2

Preparation and Storage

Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

OMIM

600892

3D Structure

ModBase 3D Structure for Q14190

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2

Product Categories/Family for anti-SIM2 antibody

Cancer Research; Tumor Biomarkers; Antibodies; Antibodies & Supporting Tools; Primary Antibodies (A-Z)

Applications Tested/Suitable for anti-SIM2 antibody

Western Blot (WB)

Application Notes for anti-SIM2 antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-SIM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIM2 purchase

MBS847753 is an antibody targeting SIM2. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SIM2. It may not necessarily be applicable to this product.

NCBI GeneID

6493

NCBI Accession #

NP_033664.2

UniProt Primary Accession #

Q14190

UniProt Protein Name

Single-minded homolog 2

UniProt Synonym Protein Names

Class E basic helix-loop-helix protein 15; bHLHe15

Protein Family

Single-minded

UniProt Gene Name

SIM2

UniProt Synonym Gene Names

BHLHE15; bHLHe15

UniProt Entry Name

SIM2_HUMAN

UniProt Comments for SIM2

SIM2: Transcription factor that may be a master gene of CNS development in cooperation with Arnt. It may have pleiotropic effects in the tissues expressed during development. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; DNA-binding

Chromosomal Location of Human Ortholog: 21q22.13

Cellular Component: nucleoplasm

Molecular Function: signal transducer activity; DNA binding; protein heterodimerization activity; transcription factor activity

Biological Process: nervous system development; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; embryonic pattern specification; cell differentiation; signal transduction; lung development

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.