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RPS6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847782

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic… More details

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Product Overview

Product Name
RPS6, Polyclonal Antibody
Full Product Name
Phospho RPS6 (Ser240) Antibody
Product Gene Name
anti-RPS6 antibody
Product Synonym Names
40S ribosomal protein S6; Phosphoprotein NP33; Phospho RPS6 (Ser240)
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Bovine, Rabbit, Dog, Rat, Chicken, Monkey, Mouse, Human
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% NaCl; pH7.3; 30% glycerol; and 0.01% sodium azide
Purity/Purification
Affinity purification
Specificity
Affinity purified rabbit polyclonal antibody to detect phosphorylation of RPS6 at Ser240 in human, mouse, rat, bovine, chicken, dog, monkey, rabbit samples
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
28,681 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (19376254..19380235, complement). Location: 9p21
OMIM
180460
3D Structure
ModBase 3D Structure for P62753
Immunogen
KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human RPS6

Product Categories/Family for anti-RPS6 antibody

Primary Antibodies; Signaling Pathways; AMPK Insulin; Leptin Signaling Antibodies; Antibodies & Supporting Tools; Phospho Specific Antibodies; Cardiovascular Research; Cancer Research; Angiogenesis Antibodies; Primary Antibodies (A-Z); Diabetes; Obesity &
Applications Tested/Suitable for anti-RPS6 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-RPS6 antibody
WB: 1:500-1:1000
IHC: 1:100-1:200
IF: 1:100-1:500

Immunocytochemistry/Immunofluorescence (ICC/IF)) of anti-RPS6 antibody

Rabbit Anti-RPS6 Polyclonal Antibody – Cat# MBS847782

Immunohistochemistry (IHC) of anti-RPS6 antibody

Rabbit Anti-RPS6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS847782

Western Blot (WB) of anti-RPS6 antibody

Rabbit Anti-RPS6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS847782

Other Notes

Small volumes of anti-RPS6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RPS6 purchase

MBS847782 is an antibody targeting RPS6. Also known as Phospho RPS6 (Ser240) Antibody. Reactive in Bovine, Rabbit, Dog, Rat, Chicken, Monkey, Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RPS6. It may not necessarily be applicable to this product.

NCBI GI #
17158044
NCBI GeneID
6194
NCBI Accession #
NP_001001.2
UniProt Primary Accession #
P62753
UniProt Secondary Accession #
P08227; P10660; Q4VBY7; Q8N6Z7
UniProt Related Accession #
P62753
GenBank Nucleotide #
NM_001010.2
NCBI Official Full Name
40S ribosomal protein S6
NCBI Official Synonym Full Names
ribosomal protein S6
NCBI Official Symbol
RPS6
NCBI Official Synonym Symbols
S6
UniProt Protein Name
40S ribosomal protein S6
UniProt Synonym Protein Names
Phosphoprotein NP33
Protein Family
30S ribosomal protein
UniProt Gene Name
RPS6
UniProt Entry Name
RS6_HUMAN
NCBI Protein Information
40S ribosomal protein S6; phosphoprotein NP33

UniProt Comments for RPS6

S6: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Belongs to the ribosomal protein S6e family.

Protein type: Translation

Chromosomal Location of Human Ortholog: 9p21

Cellular Component: polysome; small ribosomal subunit; membrane; perinuclear region of cytoplasm; dendrite; cytoplasm; nucleolus; nucleus; ribonucleoprotein complex; cytosol

Molecular Function: protein binding; structural constituent of ribosome; protein kinase binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; erythrocyte development; TOR signaling pathway; translation; viral reproduction; positive regulation of apoptosis; T cell differentiation in the thymus; gastrulation; translational termination; viral infectious cycle; glucose homeostasis; oogenesis stage; T cell proliferation during immune response; translational initiation; ribosomal small subunit assembly and maintenance; viral transcription; activated T cell apoptosis; placenta development; mitosis; mitotic cell cycle checkpoint; ribosomal small subunit biogenesis and assembly; translational elongation; cellular protein metabolic process; mRNA catabolic process, nonsense-mediated decay; insulin receptor signaling pathway; gene expression; rRNA processing; G1/S transition of mitotic cell cycle; negative regulation of apoptosis
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Research Articles on RPS6

1. High Ribosomal Protein S6 is associated with renal cell carcinoma metastases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RPS6 antibody

 Reference Product  PubMed Publications
 RPS6KB1 antibody  >4 publications with RPS6 and RPS6KB1

Pathways associated with anti-RPS6 antibody

 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Eukaryotic Translation Elongation Pathway antibodies  Eukaryotic Translation Elongation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Eukaryotic Translation Termination Pathway antibodies  Eukaryotic Translation Termination Pathway Diagram

Diseases associated with anti-RPS6 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >44 publications with RPS6 and Neoplasms
 Hypertrophy Antibodies  >19 publications with RPS6 and Hypertrophy
 Disease Models, Animal Antibodies  >11 publications with RPS6 and Disease Models, Animal
 Drug Toxicity Antibodies  >7 publications with RPS6 and Drug Toxicity
 Liver Diseases Antibodies  >6 publications with RPS6 and Liver Diseases
 Breast Neoplasms Antibodies  >6 publications with RPS6 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with RPS6 and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >4 publications with RPS6 and Neoplasms, Experimental
 Necrosis Antibodies  >4 publications with RPS6 and Necrosis
 Disease Progression Antibodies  >4 publications with RPS6 and Disease Progression

Organs/Tissues associated with anti-RPS6 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >55 publications with RPS6 and Muscle
 Blood Antibodies  >44 publications with RPS6 and Blood
 Liver Antibodies  >21 publications with RPS6 and Liver
 Brain Antibodies  >15 publications with RPS6 and Brain
 Kidney Antibodies  >9 publications with RPS6 and Kidney
 Vascular Antibodies  >7 publications with RPS6 and Vascular
 Heart Antibodies  >7 publications with RPS6 and Heart
 Bone Antibodies  >6 publications with RPS6 and Bone
 Prostate Antibodies  >5 publications with RPS6 and Prostate
 Uterus Antibodies  >4 publications with RPS6 and Uterus
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