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G-CSF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS847805

The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
G-CSF, Polyclonal Antibody
Full Product Name
Anti-G-CSF Antibody
Product Gene Name
anti-G-CSF antibody
Product Synonym Names
C17orf33; GCSF; Granulocyte colony-stimulating factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Rat, Mouse, Human
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% NaCl; pH7.3; 30% glycerol; and 0.01% sodium azide
Purity/Purification
Affinity purification
Specificity
Affinity purified rabbit polyclonal antibody to detect G-CSF expression in human, mouse and rat samples
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months
Molecular Weight
22,293 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (38171614..38174066). Location: 17q11.2-q12
OMIM
138970
3D Structure
ModBase 3D Structure for P09919
Immunogen
KLH-conjugated synthetic peptide targeting a sequence within the center region of human G-CSF

Product Categories/Family for anti-G-CSF antibody

Antibodies & Supporting Tools; Primary Antibodies (A-Z); Proteins; Enzymes; Cytokines; Growth Factors & Hormones; Antibodies to Cytokines & Growth Factors (A-Z); Cytokines; Immunology; Antibodies; Cardiovascular Research; Growth Factors; Hormones
Applications Tested/Suitable for anti-G-CSF antibody
Western Blot (WB)
Application Notes for anti-G-CSF antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-G-CSF antibody

Rabbit Anti-G-CSF Polyclonal Antibody – Cat# MBS847805

Other Notes

Small volumes of anti-G-CSF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for G-CSF purchase

MBS847805 is an antibody targeting G-CSF. Reactive in Rat, Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for G-CSF. It may not necessarily be applicable to this product.

NCBI GI #
296011057
NCBI GeneID
1440
NCBI Accession #
NP_001171618.1
UniProt Primary Accession #
P09919
UniProt Secondary Accession #
A8MXR7
UniProt Related Accession #
P09919
GenBank Nucleotide #
NM_001178147.1
NCBI Official Full Name
granulocyte colony-stimulating factor isoform d
NCBI Official Synonym Full Names
colony stimulating factor 3 (granulocyte)
NCBI Official Symbol
CSF3
NCBI Official Synonym Symbols
GCSF; CSF3OS; C17orf33
UniProt Protein Name
Granulocyte colony-stimulating factor
UniProt Synonym Protein Names
Pluripoietin
Protein Family
Granulocyte colony-stimulating factor receptor
UniProt Gene Name
CSF3
UniProt Synonym Gene Names
C17orf33; GCSF; G-CSF
UniProt Entry Name
CSF3_HUMAN
NCBI Protein Information
granulocyte colony-stimulating factor; filgrastim; lenograstim; pluripoietin

UniProt Comments for G-CSF

G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Cell cycle regulation; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q11.2-q12

Cellular Component: extracellular space

Molecular Function: enzyme binding; growth factor activity; cytokine activity; granulocyte colony-stimulating factor receptor binding

Biological Process: granulocyte differentiation; positive regulation of myeloid cell differentiation; positive regulation of protein binding; multicellular organismal development; cytokine and chemokine mediated signaling pathway; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of actin filament polymerization; positive regulation of cell proliferation; positive regulation of transcription factor import into nucleus; immune response; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on G-CSF

1. Administration of G-CSF in a dosage regimen commonly used for bone marrow donors is well tolerated and safe, and provides a signal of positive change in a task of cognitive performance in 8 patients with mild to moderate stage Alzheimer's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-G-CSF antibody

 Reference Product  PubMed Publications
 CSF2 antibody  >14 publications with G-CSF and CSF2
 CSF3R antibody  >11 publications with G-CSF and CSF3R
 MMP9 antibody  >5 publications with G-CSF and MMP9
 IL10 antibody  >4 publications with G-CSF and IL10
 CXCL12 antibody  >3 publications with G-CSF and CXCL12
 SELL antibody  >1 publications with G-CSF and SELL
 STAT3 antibody  >1 publications with G-CSF and STAT3
 CXCR4 antibody  >1 publications with G-CSF and CXCR4

Pathways associated with anti-G-CSF antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram

Diseases associated with anti-G-CSF antibody

 Disease Name  Pubmed Publications
 Disease Susceptibility Antibodies  >6 publications with G-CSF and Disease Susceptibility
 Nervous System Diseases Antibodies  >4 publications with G-CSF and Nervous System Diseases
 Neutropenia Antibodies  >3 publications with G-CSF and Neutropenia
 Leukopenia Antibodies  >2 publications with G-CSF and Leukopenia
 Anemia Antibodies  >2 publications with G-CSF and Anemia
 Leukemia, Myeloid, Acute Antibodies  >2 publications with G-CSF and Leukemia, Myeloid, Acute
 Breast Neoplasms Antibodies  >1 publications with G-CSF and Breast Neoplasms
 Peripheral Nervous System Diseases Antibodies  >1 publications with G-CSF and Peripheral Nervous System Diseases
 Pulmonary Fibrosis Antibodies  >1 publications with G-CSF and Pulmonary Fibrosis
 Brain Injuries Antibodies  >1 publications with G-CSF and Brain Injuries

Organs/Tissues associated with anti-G-CSF antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >5 publications with G-CSF and Skin
 Lung Antibodies  >3 publications with G-CSF and Lung
 Muscle Antibodies  >2 publications with G-CSF and Muscle
 Liver Antibodies  >1 publications with G-CSF and Liver
 Brain Antibodies  >1 publications with G-CSF and Brain
 Uterus Antibodies  >1 publications with G-CSF and Uterus
 Uncharacterized Tissue Antibodies  >1 publications with G-CSF and Uncharacterized Tissue
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